center Genotype and Phenotype

- DNA to RNA -

During the process of transcription ...
... a single strand of RNA is synthesized using a double stranded DNA molecule as a template.

The two strands of the DNA molecule are separated from one another, exposing the nitrogenous bases. Only one strand is actively used as a template in the transcription process, this is known as the sense strand, or template strand. The complementary DNA strand, the one that is not used, is called the nonsense or antisense strand.

The RNA sequence that is made is a direct copy of the nitrogenous bases in the sense strand. If an Guanine (G) base is part of the sequence on the sense DNA strand, then the RNA molecule has a Cytosine (C) base added to its sequence at that point. In the RNA molecule uracil (U) substitutes for Thymine (T)

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Science at a Distance
© 1997, 1998, 1999, 2000 Professor John Blamire