Gregory S. Boutis
Professor
Physics
Location: 2157d Ingersoll Hall
Phone: 718.951.5000 x2873
Fax: 718.951.4407
Email:
Gregory S. Boutis's Web site
Gregory Boutis is an experimental physicist with expertise in magnetic resonance. Prior to joining CUNY, he held a position at Northrop Grumman, where he worked on RADAR hardware and software development. Over the past 10 years or so, he and his group have focused largely on experimental studies of biological polymers. On occasion they have also done work on many-body quantum spin systems (e.g., studies of spin diffusion in a rigid lattice, spin counting). The group has collaborated in the past with laboratories at Montefiore Medical Center, MIT, NYU Langone Medical Center, Boston University, Tokyo University of Agriculture and Technology and within CUNY. The Boutis group may provide consulting expertise in all aspects of magnetic resonance(diffusion, spectroscopy, pulse sequence development)-please email us if you have interests.
Education:
Ph.D., Massachusetts Institute of Technology - 2002 (Nuclear Science and Technology)
B.A., Cornell University - 1997 (Physics)
Areas of Expertise:
Solid state NMR, diffusion NMR, MRI. Boutis' group applies these methods, as well as others, to study properties of biopolymers such as silk and elastin.
Books and Publications
A. Naito, K. Okushita, K. Nishimura, G. Boutis, A. Aoki, Akihiro, T. Asakura "Quantitative Analysis of Solid-State Homonuclear Correlation Spectra of Antiparallel β-Sheet Alanine Tetramers" J. Phys. Chem. B, 2018, 122 (10), pp 2715-2724 PDF (Books and Publications: Peer Reviewed Article) 2018
P. Rathod, M. Kaur, H.P. Ho, M.E. Louis, B. Dhital, P. Durlik, G.S. Boutis, K.J. Mark, J.I. Lee, and E.J. Chang, Quantification of desmosine and isodesmosine using MALDI-ion trap tandem mass spectrometry. Analytical and bioanalytical chemistry, pp.1-9. PDF (Books and Publications: Peer Reviewed Article) 2018
A. Papaioannou, D. S. Novikov, E. Fieremans, G. S. Boutis "Observation of structural universality in disordered systems using bulk diffusion measurement" Phys. Rev. E Rapid Communications 96, 061101. PDF (Books and Publications: Peer Reviewed Article) 2017
Asakura, T, K. Isobe, S. Kametani, O. T. Ukpebor, M. C. Silverstein, and G. S. Boutis
"Characterization of water in hydrated Bombyx mori silk fibroin fiber and films by 2H NMR relaxation and 13C solid state NMR" Acta Biomaterialia, 50, 2017, 322-333. PDF (Books and Publications: Peer Reviewed Article) 2017
B. Dhital, P. Durlik, P. Rathod, F. Gul-E-Noor, Z. Wang, C. Sun, E. J. Chang, B. Itin, and G. S Boutis "Ultraviolet radiation reduces desmosine cross-links in elastin" Biochemistry and Biophysics Reports, 10, 172-177. PDF (Books and Publications: Peer Reviewed Article) 2017
G. Boutis and R. Kausik "Comparing the efficacy of solid and magic-echo refocusing sequences : Applications to 1H NMR echo spectroscopy of shale rock" Solid State Nuclear Magnetic Resonance, 88, 22-28. PDF (Books and Publications: Peer Reviewed Article) 2017
Zhang, Y., J. Li, G.S. Boutis "The Coupled Bio-Chemo-Electro-Mechanical Behavior of Glucose Exposed Arterial Elastin" J. Phys. D: Appl. Phys. 50, 133001. PDF (Books and Publications: Peer Reviewed Article) 2017
Bilici, K., S. W. Morgan, M.C. Silverstein,Y. Wang, H.J. Sun, K. Zhang, G. S. Boutis "Mechanical, Structural, and Dynamical Modifications of Cholesterol Exposed Porcine Aortic Elastin" Biophysical Chemistry, 218: 47-57. PDF (Books and Publications: Peer Reviewed Article) 2016
Dhital, B., F. Gul-E-Noor, K. T. Downing, S. Hirsch, G. S. Boutis, "Pregnancy-Induced Dynamical and Structural Changes of Reproductive Tract Collagen" Biophysical Journal 111.1: 57-68. PDF (Books and Publications: Peer Reviewed Article) 2016
F. Gul-E-Noor, C. Singh, A. Papaioannou, N. Sinha and G. S. Boutis. "The Behavior of Water in Collagen and Hydroxyapatite Sites of Cortical Bone: Fracture, Mechanical Wear, and Load Bearing Studies" Journal of Physical Chemistry C. 119 (37), 21528-21537. PDF (Books and Publications: Peer Reviewed Article) 2015
Ming, S., R. Roopchand, E. Mananga, J-P. Amoureux, C. Qun, G. Boutis and B-W. Hu. "Theoretical calculation of a composite pulse with 8-step phase cycling for 2H broadband excitation by average Hamiltonian theory." Chinese Journal of Magnetic Resonance. 32: 373-381. (Books and Publications: Forthcoming Publications) 2015
Papaioannou, A., M. Louis, B. Dhital, H.P. Ho, E.J. Chang and G.S. Boutis. "Quantitative comparison of structure and dynamics of elastin following three isolation schemes by 13C solid state NMR and MALDI mass spectrometry." Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854.5: 391-401. PDF (Books and Publications: Peer Reviewed Article) 2015
Shen, M., R. Roopchand, E.S. Mananga, J.-P. Amoureux, Q. Chen, G.S. Boutis and B. Hu. "Revisiting Composite Pulses for Broadband 2H Excitation With 8-step Phase cycling." Solid State Nuclear Magnetic Resonance. 66: 45-48. PDF (Books and Publications: Peer Reviewed Article) 2015
Silverstein, M., K. Bilici, SW. Morgan, Y. Wang, Y. Zhang and G S. Boutis. "13C, 2H nmr studies of structural and dynamical modifications of glucose exposed porcine aortic elastin." Biophysical Journal 108: 1758-72. PDF (Books and Publications: Peer Reviewed Article) 2015
Downing, K., M. Billah, E. Raparia, A. Shah, M. Silverstein, A. Ahmad and G.S. Boutis. "The Role of Mode of Delivery on Elastic Fiber Architecture and Vaginal Vault Elasticity: A Rodent Model Study." Journal of the Mechanical Behavior of Biomedical Materials 29: 190-98. PDF (Books and Publications: Forthcoming Publications) 2014
Ukpebor, O.T., A. Shah, E. Bazov and G.S. Boutis. "Inverse Temperature Transition of Elastin Like Motifs in Major Ampullate Dragline Silk: MD Simulations of Short Peptides and NMR Studies of Water Dynamics." Soft Matter 10.5: 773-85. PDF (Books and Publications: Peer Reviewed Article) 2014
Watanabe, E., G.S. Boutis, H. Sato, S. Sekine and T. Asakura. "NMR Studies of Thermo-responsive Behavior of an Amphiphilic Poly(asparagine) Derivative in Water." Polymer 55: 278-86. PDF (Books and Publications: Peer Reviewed Article) 2014
Zelenova, Y., S.W. Morgan and G.S. Boutis. "Effects of Experimental Imperfections on a Spin Counting Experiment." Solid State Nuclear Magnetic Resonance 53: 27-37. PDF (Books and Publications: Peer Reviewed Article) 2013
Huang, J., C. Sun, O. Mitchell, N. Ng, Z. Wang and G.S. Boutis. "On the Inverse Temperature Transition and Development of an Entropic Elastomeric Force of the Elastin Mimetic Peptide [LGGVG]3,7." Journal of Physical Chemistry 136: 085101. PDF (Books and Publications: Peer Reviewed Article) 2012
Ma, X., C. Sun, J. Huang and G.S. Boutis. "Thermal Hysteresis in the Backbone and Side Chain Dynamics of the Elastin Mimetic Peptide [VPGVG]3 Revealed by 2H NMR." Journal of Physical Chemistry B 116.1: 555-64. PDF (Books and Publications: Peer Reviewed Article) 2012
Morgan, S.W., V. Oganesyan and G.S. Boutis. "Multispin Correlations and Pseudo-thermalization of the Transient Density Matrix in Solid-state NMR: Free Induction Decay and Magic Echo." Physical Review B 86: 214410. PDF (Books and Publications: Forthcoming Publications) 2012
Ma, X.C. Sun and G.S. Boutis. "Investigation of the Effect of a Variety of Pulse Errors on Spin I=1 Quadrupolar Alignment Echo Spectroscopy." Journal of Magnetic Resonance 211: 134-42. PDF (Books and Publications: Peer Reviewed Article) 2011
Sun, C. and G.S. Boutis. "Measurement of the Exchange Rate of Waters of Hydration in Elastin by 2D T2-T2 Correlation Nuclear Magnetic Resonance Spectroscopy." New Journal of Physics 13: 025026. PDF (Books and Publications: Peer Reviewed Article) 2011
Sun, C., O. Mitchell, J. Huang and G.S. Boutis. "NMR Studies of Localized Water and Protein Backbone Dynamics in Mechanically Strained Elastin." Journal of Physical Chemistry B 115.47: 13935-42. PDF (Books and Publications: Peer Reviewed Article) 2011
Sun, C. and G.S. Boutis. "Investigation of the Dynamical Properties of Water in Elastin by Deuterium Double Quantum Filtered NMR." Journal of Magnetic Resonance 205: 86-92. PDF (Books and Publications: Peer Reviewed Article) 2010
Sun, C. and G.S. Boutis. "Simulation Studies of Instrumental Artifacts on Spin I=1 Double Quantum Filtered NMR Spectroscopy." Journal of Magnetic Resonance 205: 102-08. PDF (Books and Publications: Peer Reviewed Article) 2010
Boutis, G.S., C. Renner, T. Isahkarov, T. Islam, L. Kannangara, P. Kauer, E. Mananga, A. Ntekim, Y.S. Rumala and D. Wei. "High Resolution Q-Space Imaging Studies of Water in Elastin." Proceedings of the 9th International Bologna Conference on Magnetic Resonance in Porous Media (MRMP9) Cambridge, Mass. (Books and Publications: Peer Reviewed Article) 2008
Mananga, E.S., C.D. Hsu, S. Ishmael, T. Islam and G.S. Boutis. "Probing the Validity of Average Hamiltonian Theory for Spin I=1, 3/2 and 5/3 Nuclei by Analyzing a Simple Two Pulse Sequence." Journal of Magnetic Resonance 193: 10-22. (Books and Publications: Peer Reviewed Article) 2008
Boutis, G.S., C. Renner, T. Isahkarov, T. Islam, L. Kannangara, P. Kauer, E. Mananga, A. Ntekim, Y.S. Rumala and D. Wei. "High Resolution Q-Space Imaging Studies of Water in Elastin." Biopolymers 87.5-6: 352-59. (Books and Publications: Peer Reviewed Article) 2007
Mananga, E.S., R. Roopchand, Y.S. Rumala and G.S. Boutis. "On the Application of Magic Echo Cycles for Quadrupolar Echo Spectroscopy of Spin-1 Nuclei." Journal of Magnetic Resonance 185: 28. (Books and Publications: Peer Reviewed Article) 2007
Mananga, E.S., Y.S. Rumala and G.S. Boutis. "Finite Pulse Width Artifact Suppression in Spin-1 Quadrupolar Echo Spectra by Phase Cycling." Journal of Magnetic Resonance 181: 296-303. PDF (Books and Publications: Peer Reviewed Article) 2006
Boutis, G.S., D. Greenbaum, H.J. Cho, C. Ramanathan and D.G. Cory. "Spin Diffusion of Two-Spin Correlated States in a Dielectric Crystal." Physical Review Letters 92: 13. PDF (Books and Publications: Peer Reviewed Article) 2004
Boutis, G.S., P. Cappellaro, H. Cho, C. Ramanathan and D.G. Cory. "Pulse Error Compensating Symmetric Magic Echo Trains." Journal of Magnetic Resonance 161: 132-37. PDF (Books and Publications: Peer Reviewed Article) 2003
Ramanathan, C., H. Cho, P. Cappellaro, G.S. Boutis and D.G. Cory. "Encoding Multiple Quantum Coherences in Non-Commuting Bases." Chemical Physics Letters 369: 311-17. PDF (Books and Publications: Peer Reviewed Article) 2003
Ramanathan, C., H. Cho, P. Cappellaro, G.S. Boutis and D.G. Cory. "Exploring Large Nuclear Spin Systems in the Solid State Using NMR." Conference Proceedings of the 6th International Conference on Quantum Communication, Measurement and Computing. Eds. J. Shapiro and O. Hirota. Rinton Press. (Books and Publications: Peer Reviewed Article) 2003
Awards, Honors and Fellowships
NIH SC1 grant, for "NMR Studies of the Effects of Mode of Birth on Vaginal Elastin." $1,099,000; four years. (Grants and Fellowships) 2013
Boutis, Gregory and Vadim Oganeysian. Round 16 CUNY Collaborative Incentive Research Grant, for "Spin Diffusion: Quantum Coherence, Disorder, Reduced Dimensionality." $29,786; two years. (Grants and Fellowships) 2009
NIH SC1, for "Probing Dynamics of Water in Elastin by Q-Space Imaging and Multiple Quantum NMR." $1,064,783; four years. (Grants and Fellowships) 2009
NSF grant, for "CAREER: Integrating Education and Research in NMR Structure-Function Studies of Mechanically Strained Elastin." $485,762; five years. (These funds had to be returned to NSF due to a PI developmental overlap with a funded NIH SC1 proposal.) (Grants and Fellowships) 2009
PSC CUNY Year 39, for "Probing Dynamics and Structure of Mechanically Stressed Elastin via Q-Space Imaging and Multiple Quantum NMR." $3,880; one year. (Grants and Fellowships) 2009
NIH MBRS S06, for "High Resolution Q-Space NMR Imaging of Elastin." $381,440; two years. (Grants and Fellowships) 2006
PSC-CUNY Year 36, for "High Resolution Nuclear Magnetic Resonance Q-Space Imaging of Elastin." One year. (Grants and Fellowships) 2006
