Education:
Ph.D., University of Washington - 1972 (Genetics)
B.A., University of California - Los Angeles - 1967 (Bacteriology)
Areas of Expertise:
Nishiura's lab studies the developmental biology and genetics of mosquitoes. Cutting-edge techniques of gene cloning, imaging and RNAi techniques are used to study the mechanisms that control mosquito metamorphosis. This information will be used to develop new and novel methods of controlling mosquito populations and mosquito-borne diseases. They will also be used to investigate the evolution of cis acting elements that control gene expression during development.
Books and Publications
Mercedes, Maria, Dalery Grullon, Suela Karaumuca and James T Nishiura. "Injection of Aedes aetypti Larvae With dsRNAs Results in Defects in Midgut and Cuticle Metamorphosis." Submitted. (Books and Publications: Forthcoming Publications) 2010
Ray, K., M. Mercedes, D. Chan, C.Y. Choi and J.T. Nishiura. "Growth and Differentiation of the Larval Mosquito Midgut." Journal of Insect Science 9, July 15: 55. (Books and Publications: Peer Reviewed Article) 2009
Nishiura, J.T., Cynthia Burgos, Samuel Aya, Yekaterina Goryacheva and Wingyin Lo. "Modulation of Larval Nutrition Affects Midgut Neutral Lipid Storage and Temporal Pattern of Transcription Factor Expression During Mosquito Metamorphosis." Journal of Insect Physiology 53: 47-58. (Books and Publications: Peer Reviewed Article) 2007
Nishiura, J.T., K. Ray and J. Murray. "Expression of Nuclear Receptor-transcription Factor Genes During Aedes aegypti Midgut Metamorphosis and the Effect of Methoprene on Expression." Insect Biochemistry and Molecular Biology 35: 561-73. (Books and Publications: Peer Reviewed Article) 2005
Nishiura, J.T., P. Ho and K. Ray. "Methoprene Interferes With Mosquito Midgut Remodeling During Metamorphosis." Journal of Medical Entomology 40: 498-507. (Books and Publications: Peer Reviewed Article) 2003
"Coordinated Morphological Changes in Midgut, Imaginal Discs, and Respiratory Trumpets During Metamorphosis of Aedes aegypti (Diptera: Culicidae)." Annals of the Entomological Society of America 95: 498-504. (Books and Publications: Peer Reviewed Article) 2002
Nishiura, J.T. and D. Smouse. "Nuclear and Cytoplasmic Changes in the Culex Pipiens (Diptera: Culicidae) Alimentary Canal During Metamorphosis and Their Relationship to Programmed Cell Death." Annals of the Entomological Society of America 93: 282-90. (Books and Publications: Peer Reviewed Article) 2000
Awards, Honors and Fellowships
NIH Grant, for "Genetic Analysis of Mosquito Metamorphosis," 2009-13. (Grants and Fellowships) 2009
Year 2 of NIH-Score Grant. (Grants and Fellowships) 2007
