Andrzej A. Jarzecki
Associate Professor
Chemistry and Biochemistry
Location: 228 Ingersoll Hall Extension
Phone: 718.951.5000 x2822
Fax: 718.951.4607
Email:
Andrzej Jarzecki joined Brooklyn College in 2004. Prior to that, he was postdoctoral fellow with Thomas G. Spiro at Princeton University, and postdoctoral fellow with Ernest R. Davidson at Indiana University, Bloomington.
Education:
Ph.D., University of Arkansas - 1997 (Physical / Theoretical Chemistry)
Areas of Expertise:
Theoretical: prediction of molecular and spectroscopic properties (UV, infrared, Raman and resonance Raman) of molecules with a special focus on transition and heavy metal compounds. Various applications of electronic structure calculations to enhance understanding of the structure and function of metals essential for life and the toxicity of heavy metals. His research interests and computational applications span areas of modern chemistry, biochemistry, geochemistry and environmental science.
Books and Publications
N. Curado, N. Gimenez, K. Miachin, M. Aliaga-Lavrijsen, M.A. Cornejo, A.A. Jarzecki, and M. Contel,
ChemMedChem, 14, 1-11 (Books and Publications: Article (Peer-reviewed)) 2019
M.T. Wlodarczyk, S.A. Dragulska, O. Camacho-Vanegas, P.R. Dottino, A.A. Jarzęcki, J.A. Martignetti, and A.J. Mieszawska, ACS Biomater. Sci. Eng., 4(2), pp 463-467 (Books and Publications: Article (Peer-reviewed)) 2018
Łakomska, I., M. Babinska, A. Wojtczak, A. Kozakiewicz, J. Sitkowski and Andrzej A. Jarzecki "Experimental and Theoretical Investigation of the Complexation of 5-methyl-7-isobutyl-1,2,4- triazolo[1,5-a]pyrimidine with Platinum(II) Ions" New. J. Chem. 41, 7775-7782 (Books and Publications: Article (Peer-reviewed)) 2017
Kruft, Bonnie. I., Richard S. Magliozzo and Andrzej A. Jarzecki. "Density Functional Theory Insights into the Role of the Methionine− Tyrosine−Tryptophan Adduct Radical in the KatG Catalase Reaction: O2 Release from the Oxyheme Intermediate." Journal of Physical Chemistry A 119: 6850-66. (Books and Publications: Article (Peer-reviewed)) 2015
Kupcewicz, Bogumiła, Andrzej A. Jarzęcki, Magdalena Małecka, Urszula Krajewska and Marek Rozalski, "Cytotoxic Activity of Substituted Chalcones in Terms of Molecular Electronic Properties." Bioorganic & Medical Chemistry Letters 24: 4260-65. (Books and Publications: Article (Peer-reviewed)) 2014
Kruft, Bonnie I., James M. Harrington, Owen W. Duckworth and Andrzej A. Jarzęcki. "Quantum Mechanical Investigation of Aqueous Desferrioxamine B Metal Complexes: Trends in Structure, Binding, and Infrared Spectroscopy." Journal of Inorganic Biochemistry 129: 150-61. (Books and Publications: Article (Peer-reviewed)) 2013
"Quantum-Mechanical Study of Lead Coordination in Sulfur-Rich Proteins: Mode and Structure Recognition in UV Resonance Raman Spectra." Journal of Physical Chemistry A 116: 571-81. (Books and Publications: Article (Peer-reviewed)) 2012
Gurusamy Balakrishnan, Andrzej A. Jarzecki, Qiang Wu, Pawel M. Kozlowski, Daojing Wang and Thomas G. Spiro. "Mode Recognition in UV Resonance Raman Spectra of Imidazole: Histidine Monitoring in Proteins." Journal of Physical Chemistry B 116: 9387-95. (Books and Publications: Article (Peer-reviewed)) 2012
Harrington, James M., Dorothy L. Parker, John R. Bargar, Andrzej A. Jarzecki, Bradley M. Tebo, Garrison Sposito and Owen W. Duckworth. "Structural Dependence of Mn Complexation by Siderophores: Donor Group Dependence on Complex Stability and Reactivity." Geochimica et Cosmochimica Acta 88: 106-19. (Books and Publications: Article (Peer-reviewed)) 2012
Harrington, James M., John R. Bargar, Andrzej A. Jarzecki, James G. Roberts, Leslie A. Sombers and Owen W. Duckworth. "Trace Metal Complexation by the Triscatecholate Siderophore Protochelin: Structure and Stability." Biometals 25: 393-412. (Books and Publications: Article (Peer-reviewed)) 2012
Zhao, Xiangbo, Abdelahad Khajo, Sanchez Jarrett, Javier Suarez, Yan Levitsky, Richard M. Burger, Andrzej A. Jarzecki and Richard S. Magliozzo. "Specific Function of the Met-Tyr-Trp Adduct Radical and Residues Arg-418 and Asp-137 in the Atypical Catalase Reaction of Catalase-Peroxidase KatG" Journal of Biological Chemistry 287: 37057-65. (Books and Publications: Article (Peer-reviewed)) 2012
"Quantum-Mechanical Calculations of Resonance Raman Intensities: The Weighted-Gradient Approximation." Journal of Physical Chemistry A 113: 2926-34. (Books and Publications: Article (Peer-reviewed)) 2009
Duckworth, O.W., J.R. Bargar, A.A. Jarzecki, O. Oyerinde, T.G. Spiro and G. Sposito. "The Exceptionally Stable Cobalt(III)-desferrioxamine B Complex." Marine Chemistry 113: 114-22. (Books and Publications: Article (Peer-reviewed)) 2009
Rajapakse, C.S.K., A. Martnez, B. Naoulou, A.A. Jarzecki, L. Surez, C. Deregnaucourt, V. Sinou, J. Schrvel, E. Musi, G. Ambrosini, G.K. Schwartz and R.A. Sanchez-Delgado. "Synthesis, Characterization, and In Vitro Antimalarial and Antitumor Activity of New Ruthenium(II) Complexes of Chloroquine." Inorganic Chemistry 48: 1122-31. (Books and Publications: Article (Peer-reviewed)) 2009
Suarez, J. K. Ranguelova, A.A. Jarzecki, J. Manzerova, V. Krymov, X. Zhao, S. Yu, L. Metlitsky, G.J. Gerfen and R.S. Magliozzo. "An Oxyferrous Heme/Protein-Based Radical Intermediate Is Catalytically Competent in the Catalase Reaction of M. tuberculosis catalase-peroxidase (KatG)." Journal of Biological Chemistry 284: 7017-29. (Books and Publications: Article (Peer-reviewed)) 2009
Kozlowski, P.M., J.R. Bingham and A.A. Jarzecki. "Theoretical Analysis of Core Effect in Metalloporphyrins." Journal of Physical Chemistry A 112: 12781-88. (Books and Publications: Article (Peer-reviewed)) 2008
"Lead Poisoned Zinc Fingers: Quantum-Mechanical Exploration of Structure, Coordination and Electronic Excitations." Inorganic Chemistry 46: 7509-21. (Books and Publications: Article (Peer-reviewed)) 2007
Guallar, V., A.A. Jarzecki, R.A. Friesner and T.G. Spiro. "Modeling of Ligation-Induced Helix/Loop Displacements in Myoglobin: Toward an Understanding of Hemoglobin Allostery." Journal of the American Chemical Society 128: 5427-35. (Books and Publications: Article (Peer-reviewed)) 2006
Kozlowski, P.M., T. Andruniow, A.A. Jarzecki, M. Zgierski and T.G. Sprio. "DFT Analysis of Co-alkyl and Co-adenosyl Vibrational Modes in B12-cofactors." Inorganic Chemistry 45: 5585-90. (Books and Publications: Article (Peer-reviewed)) 2006
Kozlowski, P.M., V.V. Nazarenko and A.A. Jarzecki. "DFT Analysis of Interligand Vibrations in a Hydroperoxo Complex of Cobalt Bleomycin." Inorganic Chemistry 45: 1424-26. (Books and Publications: Article (Peer-reviewed)) 2006
Anbar, A.D., A.A. Jarzecki and T.G. Spiro. "Theoretical Investigation of Iron Isotope Fractionation Between Fe(H2O)63+ and Fe(H2O)62+: Implications for Iron Stable Isotope Geochemistry." Geochimica et Cosmochimica Acta 69: 825-37. (Books and Publications: Article (Peer-reviewed)) 2005
De Angelis, F., A.A. Jarzecki, R. Car and T.G. Spiro. "Quantum Chemical Evaluation of Protein Over Heme Ligation: CO/O2 Discrimination in Myoglobin." Journal of Physical Chemistry B 109: 3065-70. (Books and Publications: Article (Peer-reviewed)) 2005
Edwards, D.C., S.B. Nielsen, A.A. Jarzecki and T.G. Spiro. "Experimental and Theoretical Vibrational Spectroscopy Studies of Acetohydroxamic Aacid and Desferrioxamine B in Aqueous Solution: Effects of pH and Iron Complexation." Geochimica et Cosmochimica Acta 69: 3237-48. (Books and Publications: Article (Peer-reviewed)) 2005
Horsman, G.P., A. Jirasek, F.H. Vaillancourt, C.J. Barbosa, A.A. Jarzecki, C. Xu, Y. Mekmouche, T.G. Spiro, J.D. Lipscomb, M.W. Blades, R.F.B. Turner and L.D. Eltis. "Spectroscopic Studies of the Anaerobic Enzyme-Substrate Complex of Catechol 1,2-dioxygenase." Journal of the American Chemical Society 127: 16882-91. (Books and Publications: Article (Peer-reviewed)) 2005
Jarzecki, A.A. and T.G. Spiro. "Porphyrin Distortion from Resonance Raman Intensities of Out-of-Plane Modes: Computation and Modeling of N-methylmesoporphyrin, a Ferrochelatase Transition State Analog." Journal of Physical Chemistry A 109: 421-30. (Books and Publications: Article (Peer-reviewed)) 2005
Jarzecki, A.A., A.D. Anbar, T.G. Spiro. "DFT Analysis of Fe(H2O)63+ and Fe(H2O)62+ Structure and Vibrations; Implications for Isotope Fractionation." Journal of Physical Chemistry A 108: 2726-32. (Books and Publications: Article (Peer-reviewed)) 2004
Venkateshrao, S., J. Yin, A.A. Jarzecki, P.G. Schultz and T.G. Spiro. "Porphyrin Distortion During Affinity Maturation of a Ferrochelatase Antibody, Monitored by Resonance Raman Spectroscopy." Journal of the American Chemical Society 126: 16361-67. (Books and Publications: Article (Peer-reviewed)) 2004
Conferences, Seminars and Symposiums
"Toxicity of Lead: Quantum-Mechanical Exploration of Lead Poisoned Zinc Fingers." American Chemical Society 40th Middle Atlantic Regional Meeting. New York. (Conferences, Seminars and Symposiums: Invited Talk) 2008
"Toxicity of Lead: Quantum-Mechanical Exploration of Lead Poisoned Zinc Fingers." Sixth Congress of International Society for Theoretical Chemical Physics. Vancouver, British Columbia, Canada. (Conferences, Seminars and Symposiums: Invited Talk) 2008
