Shaneen M. Singh
Associate Professor & Undergraduate Deputy Chairperson
Biology
Location: 217A Ingersoll Hall Extension
Phone: 718.951.5000 x1952
Fax: 718.951.4659
Email:
Shaneen Singh is an associate professor of biology. Her doctoral thesis was titled "Biochemical Studies in Growing Bamboo, Dendrocalamus strictus." Although trained as an experimental biologist, she has transitioned into the field of computational biology. The long-term research goal of her lab is to apply computer modeling to address important biological questions. She teaches courses in bioinformatics and mentors students both at the undergraduate and graduate level.
Education:
Postdoctoral Research Associate, Weill Medical College - 2004 (Computational Biology)
Postdoctoral Research Associate, University of Medicine and Dentistry - 2001 (Biochemistry & Molecular Biology)
Ph.D., Thapar Institute of Engineering and Technology (Patiala, India) - 1998 (Biotechnology)
M.S. , Punjabi University (Patiala, India) - 1993 (Biotechnology)
B.S., Punjabi University (Patiala, India) - 1991 (Life Sciences)
Areas of Expertise:
The long-term research goal of the lab is to apply computer modeling to gain insight into cellular signal transduction pathways, specifically to provide deeper insight into both the normal and aberrant subcellular targeting of domains contained in proteins which are part of macromolecular complexes and function in various biological processes.
Books and Publications
Arguelles J, Lee J, Cardenas LV, Govind S, Singh S. In Silico Analysis of a Drosophila Parasitoid Venom Peptide Reveals Prevalence of the Cation-Polar-Cation Clip Motif in Knottin Proteins. Pathogens 2023, 12, 143. https://doi.org/10.3390/pathogens12010143 (Books and Publications: Article (Peer-reviewed)) 2023
Barreto C, Silva A, Wiech E, Lopez A, San A, Singh S. Proteomic Tools for the Analysis of Cytoskeleton Proteins. Methods Mol Biol. 2022;2364:363-425. doi: 10.1007/978-1-0716-1661-1_19. PMID: 34542864. (Books and Publications: Book Chapter) 2022
Jalali, S., Yang Y., Mahmoudinobar F., Singh, S.M, Nilsson, B., and Dias, C. Using large-scale and long-time all-atom simulations to study the aggregation of amphipathic peptides into amyloid-like fibrils. Journal of Molecular Liquids 347, 118283 (Books and Publications: Article (Peer-reviewed)) 2022
Murph, M., Singh,S., and Schvarzstein, M. (2021) The Centrosomal Swiss Army Knife: A combined in silico and in vivo approach to the structure-function annotation of SPD-2 provides mechanistic insight into its functional diversity. Cell Cyle (In press; preprint available from bioRxiv 2021.04.22.441031) (Books and Publications: Article (Peer-reviewed)) 2022
Philip J, Örd M, Silva A, Singh S, Diffley JF, Remus D, Loog M, Ikui AE. Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae. Elife. 2022 Feb 10;11. doi: 10.7554/eLife.74437. PubMed PMID: 35142288; PubMed Central PMCID: PMC8830886. (Books and Publications: Article (Peer-reviewed)) 2022
San A, Palmieri D, Saxena A, Singh S. In silico study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions. Proteins. 2022 May 5;. doi: 10.1002/prot.26355. [Epub ahead of print] PubMed PMID: 35514080. (Books and Publications: Article (Peer-reviewed)) 2022
M Scarpati, Y Qi, S Govind, S Singh. A combined computational strategy of sequence and structural analysis predicts the existence of a functional eicosanoid pathway in Drosophila melanogaster. PloS one 14 (2), e0211897 (Books and Publications: Article (Peer-reviewed)) 2019
VR Aitbakieva, R Ahmad, S Singh, AV Domashevskiy. Inhibition of ricin A-chain (RTA) catalytic activity by a viral genome-linked protein (VPg) Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867(6):645-653 (Books and Publications: Article (Peer-reviewed)) 2019
Heavner, M.E., Ramroop, J., Gueguen, G., Ramrattan, G., Dolios, G., Scarpati, M., Kwiat, J., Bhattacharya, S., Wang, R., Singh, S., Govind, S. Novel Organelles with Elements of Bacterial and Eukaryotic Secretion Systems Weaponize Parasites of Drosophila. Current Biology 27(18): 2869-2877.e6, PMID: 28889977 (Books and Publications: Article (Peer-reviewed)) 2017
Scarpati M, Heavner ME, Wiech E, Singh S. Proteomic Tools for the Analysis of Cytoskeleton Proteins.Methods Mol Biol. 2016;1365:385-413. doi: 10.1007/978-1-4939-3124-8_23 (Books and Publications: Book Chapter) 2016
Martin CL, Singh SM. Identification, modeling, and characterization studies of Tetrahymena thermophila myosin FERM domains suggests a conserved core fold but functional differences.Cytoskeleton, 72: 585-596. (Books and Publications: Article (Peer-reviewed)) 2015
Wiech, E.M., H.-P. Cheng and S.M. Singh. "Molecular modeling and computational analyses suggests that the Sinorhizobium meliloti periplasmic regulator protein ExoR adopts a superhelical fold and is controlled by a unique mechanism of proteolysis." Protein Science 24: 319-27. doi: 10.1002/pro.2616 (Books and Publications: Article (Peer-reviewed)) 2015
Chavadi, S.S., U.R. Edupuganti, O. Verrgnolle, I. Fatima, S.M. Singh, C.E. Soll and L.E.N. Quadri. "Inactivation of tesA reduces cell-wall lipid production and increases drug susceptibility in mycobacteria." The Journal of Biological Chemistry 286: 24616-25 [PMID: 21592957]. (Books and Publications: Article (Peer-reviewed)) 2011
Wywial, E. and S.M. Singh. "Identification and Structural Characterization of FYVE Domain-containing Proteins of Arabidopsis thaliana." BMC Plant Biology 10: 157. (Books and Publications: Article (Peer-reviewed)) 2010
Wywial, E., J. Haven, S.R. Casjens, Y.A. Hernandez, S. Singh, E.F. Mongodin, C.M. Fraser-Liggett, B.J. Luft, S.E. Schutzer and W.G. Qiu. "Fast, Adaptive Evolution at a Bacterial Host-resistance Locus: The PFam54 Gene Array in Borrelia burgdorferi." Gene 445: 26-37. (Books and Publications: Article (Peer-reviewed)) 2009
Wywial, E., V.N. Dongre and S. Singh. "Proteomic Tools for the Analysis of Cytoskeleton Proteins." Cytoskeleton Methods and Protocols, 2nd ed., Methods in Molecular Biology Series. Ed. Ray H. Gavin. (Books and Publications: Book Chapter) 2009
Garcia, M., M. Abbasi, S. Singh and Q. He. "Role of Drosophila Gene dunc-115 in Nervous System." Invertebrate Neuroscience 7: 119-28. (Books and Publications: Article (Peer-reviewed)) 2007
Kachroo, D., S. Singh and V. Ramamurthy. "Modulation of Unsaturated Fatty Acids Content in the Algae Spirulina platensis and Chlorella minutissima in Response to Herbicide SAN 9785." Electronic Journal of Biotechnology 9. ISSN: 0717-3458. (Books and Publications: Article (Peer-reviewed)) 2006
Mulgrew-Nesbitt, A., K. Diraviyam, J. Wang, S. Singh, P. Murray, Z. Li, L. Rogers, N. Mirkovic and D. Murray. "The Role of Electrostatics in Protein-membrane Interactions. Lipid-protein Interactions." Biochimica et Biophysica Acta 176: 1812-26. (Books and Publications: Article (Peer-reviewed)) 2006
Hisert, K.B., M. MacCoss, M.U. Shiloh, K.H. Darwin, S. Singh, R.A. Jones, S. Ehrt, Z. Zhang, B.L. Gaffney, S. Gandotra, D.W. Holden, D. Murray and C. Nathan. "An EAL Domain Protein of Salmonella Controls Bacterial Survival in Mice, Anti-oxidant Defense, and Killing of Macrophages: Role of cyclic-diGMP." Molecular Microbiology 56: 1234-45. (Books and Publications: Article (Peer-reviewed)) 2005
Stahelin, R.V., B. Ananthanarayanan, N.R. Blatner, S. Singh, K.S. Bruzik, D. Murray and W. Cho. "Mechanism of Membrane Binding of the Phospholipase D1 PX Domain." Journal of Biological Chemistry 279: 54819-26. (Books and Publications: Article (Peer-reviewed)) 2004
Yu, J.W., J.M. Mendrola, A. Audhya, S. Singh, D. Keleti, D.B. DeWald, D. Murray, S.D. Emr and M.A. Lemmon. "Genome-wide Analysis of Membrane Targeting by S. cerevisiae Pleckstrin Homology (PH) Domains." Molecular Cell 13: 677-88. (Books and Publications: Article (Peer-reviewed)) 2004
Singh, S. and D. Murray. "Molecular Modeling of the Membrane Targeting of Phospholipase C Pleckstrin Homology Domains." Protein Science 12: 1934-53. (Books and Publications: Article (Peer-reviewed)) 2003
Singh, S., N. Awasthi, C. Egwuagu and B.J. Wagner. "Immunoproteasome Expression in a Non-immune Tissue, the Ocular Lens." Archives of Biochemistry and Biophysics 405: 147-53. (Books and Publications: Article (Peer-reviewed)) 2002
Awards, Honors and Fellowships
PSC-CUNY. An in silico approach to decipher the mechanism of Cdc6 interactions with key interaction partners. $3499 (2022-2023) (Grants and Fellowships) 2022
Tow Research and Creativity Grant. In silico study predicts a key role of RNA-binding domains 3 and 4 in Nucleolin-miRNA interactions. $2500. (Grants and Fellowships) 2022
PSC-CUNY. Building a Nek10 interactome: A cancer-focused computational approach to map Nek10's interacting protein partners. S. Singh. $3500, 1 year (2021-2022) (Grants and Fellowships) 2021
In silico modeling of p27Kip1 with the Brk SH3 domain and variants to develop a p27drug candidate for treatment in cancer. Concarlo Holdings LLC., $11,188, 1 year. (Grants and Fellowships) 2018
PSC-CUNY Traditional A : Role of the Gab family pleckstrin homology domains in cancer: A computational study 1 yr ( 2018-2019) $2999 (Grants and Fellowships) 2018
PSC-CUNY Traditional A : Uncovering the membrane targeting mechanism of Class I myosin proteins: A computational study $2570, 1 year (2017-2018) (Grants and Fellowships) 2017
In silico modeling of p27Kip1 with the Brk SH3 domain and variants to develop a p27drug candidate for treatment in cancer. Concarlo Holdings LLC., $15,000, 1 year (2016-2017) (Grants and Fellowships) 2016
NSF grant, for "Arabidopsis 2010." $740,100; 2006-10. (Grants and Fellowships) 2006
Conferences, Seminars and Symposiums
Aksoy, M., and Singh, S. Homology modeling of PH domains of Chlamydomonas reinhardtii. Oral presentation, International Halich congress on multidisciplinary scientific research, Istanbul, Türkiye January 2023 (online) (Conferences, Seminars and Symposiums: Contributed Talk) 2023
Chhabra, D. and Singh, S. A Computational Investigation of Histone-Deacetylase-6's role in Osteoclast Dislodgement from Bone. Experimental Biology 2022. Philadelphia, April 2-5, 2022 (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Edwards, J., San, A., and Singh, S. Nucleolin's Role in the Biogenesis of Pri-miRNA 16 by the Microprocessor Complex: An In silico Approach. Experimental Biology 2022. Philadelphia, April 2-5, 2022 (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Jalali.,S. Yang,Y., Mahmoudinobar,F., Singh,S. Nilsson,B., and Dias, C. Aggregation of amphipathic peptides into amyloid-like fibrils. Session F06: Physics of Proteins II: Intrinsically Disordered Proteins & Protein Folding, APS Annual Meeting, Chicago, March 2022
(Conferences, Seminars and Symposiums: Contributed Talk) 2022
San, A., Palmieri, D., Saxena, A., and Singh, S. In silico characterization of nucleolin -miRNA interactions. ISCB-LA SOIBIO BioNetMX, November,2022. (Conferences, Seminars and Symposiums: Conference Presentation) 2022
San, A., Palmieri, D., Saxena, A., and Singh, S. The RNA binding domains 3 and 4 of Nucleolin are predicted to be drivers of nucleolin -miRNA interactions. ASBMB|EMBO Cell Bio meeting, Washington D.C., December 2022 (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Semchenkov Pastukhov, Silva, A., and Singh, S. Prediction and characterization of putative UBA domains in human NEK10. Abstract #2879. ASBMB|EMBO Cell Bio meeting, Washington D.C., December 2022. (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Silva, A, and Singh, S. A computational characterization of a novel predicted NEK10 - MAP3K1 interaction. Abstract #2865. ASBMB|EMBO Cell Bio meeting, Washington D.C., December 2022. (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Silva, A., and Singh, S. A computational analysis of NEK10 and its novel protein-protein interaction with Hspb1. 2022 AACR Annual meeting, Virtual. (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Silva, A., and Singh, S. In-silico investigation of NEK10 and its novel protein-protein interaction with MEKK. ISCB-LA SOIBIO BioNetMX, November,2022. (Conferences, Seminars and Symposiums: Conference Presentation) 2022
Silva, A., Philip, J., Ikui, A., and Singh, S. An in-silico approach to analyze and characterize the interaction of Cdc6 with Clb2. Oral presentation, ISCB-LA SOIBIO BioNetMX, Queretero November,2022. (Conferences, Seminars and Symposiums: Contributed Talk) 2022
Chhabra, D. and Singh, S. Biocomputational Analysis of ARAP1, a GTPase-Activating-Protein Involved in Osteoclast-Mediated Bone Digestion, American Society for Biochemistry and Molecular Biology, April 2021. (Conferences, Seminars and Symposiums: Conference Presentation) 2021
San, A., Saxena,A., and Singh, S. An in silico analysis of nucleolin-mRNA and nucleolin-miRNA interactions in breast cancer to elucidate the mechanisms of NCL-RNA specificity through its four RNA binding domains. ASBMB Emerging Roles of the Nucleolus. October 2021. (Online) (Conferences, Seminars and Symposiums: Conference Presentation) 2021
San, A., Saxena,A., and Singh, S. Do all 4 NCL RNA Binding Domains play a role in mRNA target specificity? An in silico study to decipher NCL-mRNA interactions. American Association of Cancer Research Annual Meeting, April 2021 (Online) (Conferences, Seminars and Symposiums: Conference Presentation) 2021
San, A., Saxena,A., and Singh, S. Nucleolin-miRNA interactions are driven by specific elements on RNA binding domains of nucleolin: An sillico modeling and RNA-protein docking study. PDB50, American Society for Biochemistry and Molecular Biology, May 2021. (Online) (Conferences, Seminars and Symposiums: Conference Presentation) 2021
Silva, A. and Singh, S. Computational Analysis of the NEK Family of Proteins Reveals Unique Structural Features and Interactions with Other Cancer-Related Proteins, American Association for Cancer Research, April 2021. (Conferences, Seminars and Symposiums: Conference Presentation) 2021
Silva, A. and Singh, S. Computational analysis of the NEK family of proteins reveals unique structural features and interactions with other cancer-related proteins, PDB50, American Society for Biochemistry and Molecular Biology, May 2021. (Conferences, Seminars and Symposiums: Conference Presentation) 2021
Silva, A., Philip, J., Singh, S., and Ikui, A. In-silico analysis of Cdc6, Cdc4 and Clb2 protein-protein interactions during cell cycle. Eukaryotic DNA Replication & Genome Maintenance. September 2021. (Online) (Conferences, Seminars and Symposiums: Conference Presentation) 2021
Jalali, S., Yang, Y., Mahmoudinobar, F., Singh, S., and Dias, C..Protein aggregation and self-assembly into amyloid-like fibrils. Mid-Atlantic Section Fall Meeting 2020. December 2020.Virtual (Conferences, Seminars and Symposiums: Conference Presentation) 2020
Kushner, K., Chabbra, D., Patel,S., and Singh, S. Modeling the pH domains of ARAP proteins (H. sapiens) to determine their impact in cell signaling. New York Structural Biology Discussion Group Meeting, Mount Sinai School of Medicine, NY, Januray 2020. (Conferences, Seminars and Symposiums: Conference Presentation) 2020
Lopez, A., Ravich, D., and Singh,S. In silico analysis of the membrane targeting mechanism of the pleckstrin homology domains within the oncogenic Grb2-associated-binding protein family. New York Structural Biology Discussion Group Meeting, Mount Sinai School of Medicine, NY, January 2020. (Conferences, Seminars and Symposiums: Conference Presentation) 2020
S Singh, R Ahmad, E Wywial. Insights into the mechanism of recruitment of different membrane-binding domains of Arabidopsis thaliana using computational approaches. Mid-Atlantic Section Fall Meeting, December 2020. Virtual
(Conferences, Seminars and Symposiums: Conference Presentation) 2020
San, A., Saxena,A., and Singh, S. RNA binding domains of nucleolin exhibit specificity in driving nucleolin-miRNA interactions: An in silico modeling and RNA-protein docking study. American Association of Cancer Research Annual Meeting, April 2020 (Online)
(Conferences, Seminars and Symposiums: Conference Presentation) 2020
San, A., Saxena, A., and Singh, S. In silico modeling of RNA binding domains (RBDs) of nucleolin and miRNA interactions. New York Structural Biology Discussion Group Meeting, Mount Sinai School of Medicine, NY, January 2020. (Conferences, Seminars and Symposiums: Conference Presentation) 2020
San, A., Saxena, A., and Singh, S. In Silico Predictions of Nucleolin-miRNA interactions via Molecular Modeling and Docking. ASBMB|EMBO Cell Bio meeting, December 2020 Virtual (Conferences, Seminars and Symposiums: Conference Presentation) 2020
Silva, A. and Singh, S. Computational Analysis of the NEK Family of Proteins Reveals Unique Structural Features and Interactions with Other Cancer-Related Proteins, American Association for Cancer Research, April 2020. (Conferences, Seminars and Symposiums: Conference Presentation) 2020
Silva, A., and Singh, S. A family-wide computational analysis of the catalytic domains of the Never-In-Mitosis A-Like (NEK) Protein Kinases. 2020 ASCB | EMBO Cell Bio Meeting, December 2020 Virtual. (Conferences, Seminars and Symposiums: Conference Presentation) 2020
Lopez, A., Awan, E., Zaheer,A., and Singh, S. .In silico analysis of the membrane targeting mechanism of the pleckstrin homology domains within the oncogenic Grb2-associated-binding protein family. American Association of Cancer Research Annual Meeting, Atlanta,GA. (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Aitbakieva,V.R. , Ahmad, R., Domashevskiy,A., and Singh,S.. Turnip mosaic virus genome-linked protein inhibits in vitro activity of ricin A-chain. EXPERIMENTAL BIOLOGY 2019, Orlando, Florida, USA (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Arguelles, J. and Singh, S. Structurally Conserved CpC Clip Motif and It's Role in the Infective Success of Drosophila Parasitoid, Leptopilina heterotoma. New York Structural Biology Meeting, New York. January, 2019 (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Arguelles,J., Govind,S., and Singh,S. Structural analysis of LhKNOT, a venom peptide of Drosophila prasitoid, Leptopilina heterotoma, reveals potential role of heparin-binding structural motif in antimicrobial activity of knottin proteins, Entomological Society of America, St. Louis, MO. November 2019 (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Ravich,D., Patel, S, Singh, S.,Kushnir, K.., Govind, S., and Singh,S. Identifying the function and model of novel proteins found in Leptopilina heterotoma venom in space and ground variants. New York Structural Biology Discussion Group Meeting, The Roy and Diana Vagelos Education Center at Columbia Medical School, New York. August, 2019
(Conferences, Seminars and Symposiums: Conference Presentation) 2019
San, A., Saxena, A., and Singh, S. In silico modeling of RNA binding domains (RBDs) of nucleolin and miRNA interactionsNew York Structural Biology Discussion Group Meeting, The Roy and Diana Vagelos Education Center at Columbia Medical School, New York. August, 2019. (Conferences, Seminars and Symposiums: Conference Presentation) 2019
San, A., Saxena,A., and Singh,S. In silico modeling of RNA Binding Domains (RBDs) of nucleolin and miRNA interactions. American Association of Cancer Research Annual Meeting, Atlanta, GA. (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Shah, S., Govind, S. and Singh, S. Characterization of the Diedel protein in the venom of Leptopilina heterotoma. New York Structural Biology Discussion Group Meeting, The Roy and Diana Vagelos Education Center at Columbia Medical School, New York. August, 2019. (Conferences, Seminars and Symposiums: Conference Presentation) 2019
Embrione, V., Scarpati, M. , . Uzzel, Z..D., Ahmad,R., De Sury, F.A., Sheetz,T. J. , Coppola,V. ,Singh, S. M., Saxena, A. D., Croce,C. M., and Palmieri, D. A human scFv as a tool to understand the biogenesis of a subset of oncogenic microRNAs. American Association of Cancer Research Annual Meeting, Chicago, IL. (Conferences, Seminars and Symposiums: Conference Presentation) 2018
Arguelles, J. and Singh, S. Computational analysis of a Knottin like protein from the wasp, Leptopilina heterotoma. New York Structural Biology Meeting, New York. August, 2018 (Conferences, Seminars and Symposiums: Conference Presentation) 2018
Durmus, C.A, and Singh, S. A family-wide computational analysis of the catalytic domains of the Never In Mitosis A-like kinase (NEK) proteins. American Association of Cancer Research Annual Meeting, Chicago, IL. (Conferences, Seminars and Symposiums: Conference Presentation) 2018
Lee, J., and Singh, S. Elucidating the membrane binding mechanism of the unconventional myosin, myosin 1D, 2018 ASCB |EMBO , SanDiego, CA. (Conferences, Seminars and Symposiums: Conference Presentation) 2018
Ahmad, R. and Singh, S. The Modeling and Classification of BAR Domains in Arabidopsis thaliana. The New York Structural Biology Discussion Group 12th Winter Meeting, New York. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Barreto, C., and Singh, S. Computational analysis of the membrane targeting domains of the phospholipase D family in Arabidopsis thaliana. 2017 ASCB | EMBO Meeting, Philadelphia, PA. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Barreto, C., Francisco, G., Heavner, M.E. , Govind, S., and Singh, S. Bioinformatic study of wasp venom metalloendopeptidases involved in immunosuppressant parasitism. The New York Structural Biology Discussion Group 12th Winter Meeting, New York. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Begum, K., Steinberg, R., Saxena, A., and Singh, S. Delineating the role of multiple copies of RNA binding domains in human nucleolin and its homologs using a computational approach. American Association of Cancer Research Annual Meeting, Washington DC (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Gruffat, D. and Singh,S. Uncovering the Membrane Targeting Mechanism of Human Unconventional Class I Myosins: A Computational Study. American Association of Cancer Research Annual Meeting, Washington DC (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Gruffat, D. and Singh,S. Uncovering the Membrane Targeting Mechanism of Human Unconventional Class I Myosins: A Computational Study. Biophysical Society Annual Meeting, San Diego, CA. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Jerliu, A., Heavner, M.E., Govind, S., and Singh, S. Computational modeling and characterization of Diedel proteins that regulate highly-conserved immune signaling. American Association of Cancer Research Annual Meeting, Washington DC (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Kamrun B, Steinberg,R. ,Saxena, A. and Singh,S. Delineating the Role of Multiple Copies of RNA Binding Domains in Human Nucleolin and its Homologs Using a Computational Approach. The New York Structural Biology Discussion Group 12th Winter Meeting, New York
(Conferences, Seminars and Symposiums: Conference Presentation) 2017
Lim, H., Heavner, M.E. , Govind, S., and Singh, S. Modeling Potential Rho GTPase Activating Proteins in Virus Like Proteins of Immune-Evasive Parasitoid L. heterotoma. The New York Structural Biology Discussion Group 12th Winter Meeting, New York. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Murph, M, Singh, S, and Schvazrstein, S. 2017 Structural and functional analyses of the C. elegans Spindle-Defective Protein 2 ASH domain ASCB | EMBO Meeting, Philadelphia, PA. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Rahimah Ahmad, Tasnim Azad, Carlos Barreto, Kamrun Begum, Mahlaqa Butt, Daniel Gruffat, Aulon Jerliu, Jonathan Kwiat, Mikaela Murph, Katherine A. Rivera Gómez, Barry Honig, Andrea Califano, Shaneen Singh, Diana Murray. Columbia University?s Center for Cancer Systems Therapeutics (CaST) 2017 Scholars Program: A synergistic partnership with students from Brooklyn College, CUNY. American Association of Cancer Research Annual Meeting, Washington DC (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Wiech, E., Cheng, H., and Singh, S. Computational analyses of the ExoS protein, a component of Sinorhizobium meliloti ExoR-ExoS/ChvI pathway. 2017 ASCB | EMBO Meeting, Philadelphia, PA. (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Govind, S., Heavner, M.E., Ramroop, J., Wey,, B., Singh,, S. Molecular analysis of immune-suppressive virus-like particles from Cynipid wasp Leptopilina heterotoma, a generalist parasite of Drosophila spp. (XXV International Congress in Entomology, Orlando. Symposium Title: Interactions Between the Insect Immune System and Parasites) (Conferences, Seminars and Symposiums: Contributed Talk) 2016
Heavner, M., Ramroop, R., Ramrattan, G., Dolios, G., Scarpati, M., Qiu, W.-G., Wang, R., Singh, S., Govind, S. Molecular analyses of immune-suppressive virus-like particles from a Drosophila parasitic wasp suggest cell-specific activities and a hybrid biotic particle nature. (The Allied Genetics Conference (GSA) and 57th Annual Drosophila Research Conference, Orlando, Immunity and Pathogenesis Platform Session, Presentation No. 228) (Conferences, Seminars and Symposiums: Conference Presentation) 2016
Heavner, M.E., Ramroop, J., Ramrattan, G., Dolios, G., Crissman, J., Scarpati, M., Kwiat, J., Miller, E.A., Qiu, W., Wang, R., Singh, S., Govind, S. Functional multi 'omics' uncover a novel organelle with both prokaryotic and eukaryotic proteins that weaponizes parasites of Drosophila .American Society for Cell Biology (ASCB) Annual Meeting, San Francisco, Host-Pathogen Interactions Session, Poster No. P2422 (Conferences, Seminars and Symposiums: Conference Presentation) 2016
Singh, S. Using template-based modeling and bioinformatics to gain insight into the function of various protein domains/proteins. 44th ACS Middle Atlantic Regional Meeting (MARM), Riverdale, NY. (Conferences, Seminars and Symposiums: Invited Talk) 2016
Heavner, M.E., Singh, S.M., Govind, S. Venomics: Wasp-induced immune modulation in D. melanogaster (NIH Minority Health and Health Disparities Grantees' Conference) (Conferences, Seminars and Symposiums: Conference Presentation) 2014
Heavner, Mary E., Shubha Govind and Shaneen Singh. "Predictive Venomics: Using Hybrid Modeling to Gain Functional Insights Into a Novel, Predicted GTPase From an Immune Suppressive Wasp." 58th Annual Meeting of the Biophysical Society. San Francisco. (Conferences, Seminars and Symposiums: Conference Presentation) 2014
Steinberg, Ruchama, David Plaza, Keith Bernis, Joseph Karbariti, Nathan Morris, Leonid Shosin, Anastasia Veresciac and Shaneen Singh. "Computational Analyses of Nek Family Proteins: Modeling, Evolutionary, and Mutational Studies." Innovative Exploration: Undergraduate Research in New York State's Public Higher Education System. CUNY and SUNY Forum. Albany, N.Y. (Conferences, Seminars and Symposiums: Conference Presentation) 2014
"Using Homology Modeling and Bioinformatics to Gain Insight Into the Function of Various Protein Domains." Seminar Series, Molecular and Cellular Biology Program in the School of Graduate Studies. SUNY Downstate. Brooklyn, N.Y. (Conferences, Seminars and Symposiums: Invited Talk) 2013
Heavner, Mary E., Gwenelle Guenguen, Shubha Govind and Shaneen M. Singh. "Dynamin-like proteins from the VLPs of the parasitoid wasp Leptopilina heterotoma: Unexpected domain architectures." 7th Summer Meeting, New York Structural Biology Discussion Group. New York, Aug. 9. (Conferences, Seminars and Symposiums: Conference Presentation) 2012
Itrat, F. and Singh S. Genome Computational Analysis of GRAM domains in the model plant Arabidopsis thaliana. RECOMB 2012, the 16th Annual International Conference on Research in Computational Molecular Biology, Barcelona, Spain. (Conferences, Seminars and Symposiums: Conference Presentation) 2011
Qi, Y. and S. Singh. "Computational Modeling of Cyclooxygenase in Drosophila." 51st Annual Meeting of the American Society for Cell Biology. Denver. (Conferences, Seminars and Symposiums: Conference Presentation) 2011
Weich, E., H. Yu, H. Cheng and S.M. Singh. "Computational Analysis of Sinorhizobium meliloti ExoR Protein." 50th Annual Meeting of the American Society for Cell Biology. Philadelphia, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2010
Wywial, E., N. Dongre and S.M. Singh. "Functional Characerization of Tubby Domains of Arabidopsis thaliana Using Computational Methods." 54th Annual Meeting of the Biophysical Society. San Francisco, February. (Conferences, Seminars and Symposiums: Conference Presentation) 2010
Brasse, D., R. Abdel-Naby and S. Singh. "Genome-wide Modeling and Analysis of BAR Domains in Arabidopsis thaliana." 53rd Annual Meeting of the Biophysical Society. Boston, February. (Conferences, Seminars and Symposiums: Conference Presentation) 2009
Tsoi, S., S.F.P. Mehr and S. Singh. "Functional Annotation of the MyTH4 and FERM Domains of Tetrahymena thermophila MYO1 Using Bioinformatics Tools." 49th Annual Meeting of the American Society for Cell Biology. San Diego, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2009
Wywial, E. and S. Singh. "Computational Analysis of the Membrane Targeting Domains of the Plant-specific PRAF Proteins." International Conference on Bioinformatics and Computational Biology. Paris, June. (Conferences, Seminars and Symposiums: Conference Presentation) 2009
Dongre, N., D.Y. Brogun and S. Singh. "Functional Characterization of Arabidopsis Tubby Domains Using Computational Methods." 48th Annual Meeting of the American Society for Cell Biology. San Francisco, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2008
Wywial, E. and S. Singh. "Computational Analyses of Phosphoinositide-binding Domains in Arabidopsis thaliana." 48th Annual Meeting of the American Society for Cell Biology. San Francisco, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2008
Dongre, N. and S. Singh. "OCLC, a Novel Organism Centric Literature Curation Database." 47th Annual Meeting of the American Society for Cell Biology. Washington, D.C., December. (Conferences, Seminars and Symposiums: Conference Presentation) 2007
Koors, P., A. Frank, M. Saint-jour and S. Singh. "Genome-wide Analysis of the Pleckstrin Homology Domains of Dictyostelium discodieum." 47th Annual Meeting of the American Society for Cell Biology. Washington, D.C., December. (Conferences, Seminars and Symposiums: Conference Presentation) 2007
Lai, M., T. Shuk, Y. Leon and S. Singh. "Functional Annotation of the MyTH4 Domain Using Bioinformatics Tools." 47th Annual Meeting of the American Society for Cell Biology. Washington, D.C., December. (Conferences, Seminars and Symposiums: Conference Presentation) 2007
Silkov, A., E. Wywial, N. Mirkovic, S. Singh and D. Murray. "Proteomic Analysis of Peripheral Membrane Proteins in the A. thaliana Genome." Plant Genomes, Cold Spring Harbor Laboratories. Cold Spring, N.Y., March. (Conferences, Seminars and Symposiums: Contributed Talk) 2007
Wywial, E. and S. Singh. "Genome-wide Characterization of Two Phosphoinositide Binding Domains of the Arabidopsis thaliana Using High-throughput and Manual Computational Analyses." 47th Annual Meeting of the American Society for Cell Biology. Washington, D.C., December. (Conferences, Seminars and Symposiums: Conference Presentation) 2007
Wywial, E., A. Silkov, D. Murray and S. Singh. "Genome-wide Analysis of the FYVE Domains of Arabidopsis thaliana." 15th Annual International Conference on Intelligent Systems for Molecular Biology & 6th European Conference on Computational Biology. Vienna, July. (Conferences, Seminars and Symposiums: Conference Presentation) 2007
Wywial, E. and S. Singh. "Molecular Modeling Studies of the Pleckstrin Homology Domains of the Gab Family of Proteins." 46th Annual Meeting of the American Society for Cell Biology. San Diego, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2006
Newell, S.A., J. Polle and S. Singh. "Molecular Modeling Studies of Chlamydomonas reinhardtii LHC Proteins." 45th Annual Meeting of the American Society for Cell Biology. San Francisco, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2005
Singh, S.M. and D. Murray. "Role of Non-specific Electrostatics in the Membrane Targeting of Pleckstrin Homology Domains." Biophysical Journal (Annual Meeting Abstracts) 2004: 2906-Pos. (Conferences, Seminars and Symposiums: Conference Presentation) 2004
Singh, S.M., Z.D. Li and D. Murray. "Membrane Targeting of Phospholipase C C2 Domains." Biophysical Journal (Annual Meeting Abstracts) 2003: 270-Pos. (Conferences, Seminars and Symposiums: Conference Presentation) 2003
Singh, S.M. and D. Murray. "Molecular Modeling Studies of Phospholipase C PH Domains." 42nd Annual Meeting of the American Society for Cell Biology. San Francisco, December. (Conferences, Seminars and Symposiums: Conference Presentation) 2002
