Peter N. Lipke

Education:

Ph.D., University of California - Berkeley - 1976 (Biochemistry)

B.S., University of Chicago - 1971 (Chemistry)

Areas of Expertise:

Lipke's lab recently discovered that amyloid formation at the cell surface activates yeast cell adhesion proteins, which has led to the lab's research in the role of amyloids in host-pathogen interactions. This idea is part of long-term studies of glycoprotein structure and function, bioinformatics, structure and biogenesis of fungal cell walls, and anti-fungal drug discovery. The lab's studies are informed by bioinformatic studies in protein structure and evolution.

Doctoral Rotation Projects:

Graduate students are learning bioinformatics to find amyloid sequences in cell adhesion proteins, and then test whether they form amyloids in vitro and in vivo. Their most recent rotation projects were to determine amyloid function in new models of microbial biofilms and fungal-host interactions, and to create plasmids to express amyloid and non-amyloid forms of cell adhesion proteins. Depending on the interests of the students, rotation projects can include molecular biology, cell biology, physical biochemistry and/or bioinformatics. Students learn microbiology.

Books and Publications

Alsteens, D., C.B. Ramsook, P.N. Lipke and Y.F. Dufrene. "Unzipping of a Functional Microbial Amyloid." ACS Nano. PMID 22924880. In press. (Books and Publications: Forthcoming Publications) 2012

Beaussart, A., D. Alsteens, S. El Kirat, P.N. Lipke, P. van Dijk and Y.F. Dufrene. "Single Molecule Imaging and Functional Analysis of Als Adhesions and Mannans During Candida albicans Morphogenesis." ACS Nano. http://pubs.acs.org/doi/abs/10.1021/nn304505s. (Books and Publications: Peer Reviewed Article) 2012

El-Kirat-Chatel, S., A. Beaussart, D. Alsteens, D.N. Jackson, P.N. Lipke and Y.F. Dufrene. "Nanoscale Analysis of Caspofungin-induced Cell Surface Remodeling in Candida albicans." Nanoscale. In press. (Books and Publications: Forthcoming Publications) 2012

Gilchrist, K.B., M.C. Garcia, R. Sobonya, P.N. Lipke and S.A. Klotz. "New features of candidiasis in humans: Amyloid formation by fungi and deposition of Serum Amyloid P component by the host." The Journal of Infectious Diseases. doi: 10.1093/infdis/jis464; featured article. (Books and Publications: Peer Reviewed Article) 2012

Heinisch, J.J., P.N. Lipke, A. Beaussart, S. El Kirat Chatel, V. Dupres, D. Alsteens and Y.F. Dufrene. "Atomic Force Microscopy: Looking at Mechanosensors on the Cell Surface." Journal of Cell Science. PMID: 23077172. In press. (Books and Publications: Forthcoming Publications) 2012

Lipke, P.N., M.C. Garcia, D. Alsteens, C.B. Ramsook, S.A. Klotz and Y.F. Dufrêne. "Strengthening Relationships: Amyloids Create Adhesion Nanodomains in Yeasts." Trends in Microbiology 20: 59-65. http://dx.doi.org/10.1016/j.tim.2011.10.002 Cover feature and illustration. (Books and Publications: Peer Reviewed Article) 2012

Oli, M.W., H.N. Otoo, P.J.Crowley, K.P. Heim, M.M. Nascimento, C.B. Ramsook, P.N.Lipke and L.J. Brady. "Functional amyloid formation in Streptococcus mutans." Microbiology. PMID 23082034. In press. (Books and Publications: Forthcoming Publications) 2012

Garcia, M.C., J.T. Lee, C.B Ramsook, D. Alsteens and Y.F Dufrene. "A Role for Amyloid in Cell Aggregation and Biofilm Formation." PLoS One 6: e17632. doi:10.1371/journal.pone.0017632. PMC3050909. (Books and Publications: Peer Reviewed Article) 2011

Xie, X., W. Qiu and P.N. Lipke. "Accelerated and Adaptive Evolution of Yeast Sexual Adhesins." Molecular Biology and Evolution. doi: 10.1093/molbev/msr145. (Books and Publications: Peer Reviewed Article) 2011

Alsteens, D., M.C. Garcia, P.N. Lipke* and Y. Dufrene* (*co-corresponding authors). "Force-induced Formation and Propagation of Adhesion Nanodomains in Living Fungal Cells. Proceedings of the National Academy of Sciences, USA 107: 20744-49 (featured in "In This Issue"). (Books and Publications: Peer Reviewed Article) 2010

Frank, A.T., C. Ramsook, H.N. Otoo, C. Tan, G. Soybelman, J.M. Rauceo, N.K. Gaur, Stephen A. Klotz and P.N. Lipke. "Structure and Function of Glycosylated Tandem Repeats from Candida albicans ALS Adhesins." Eukaryotic Cell 9: 405-14. Cover illustration. (Books and Publications: Peer Reviewed Article) 2010

Gonzalez, M., N. Goddard, C. Hicks, R. Ovalle, C.K. Jue and P.N. Lipke. "A Screen for Deficiencies in GPI-Anchorage of Wall Glycoproteins in Yeast." Yeast 27: 583-96. (Books and Publications: Peer Reviewed Article) 2010

Klotz, S.A. and P.N. Lipke. "The Perfect Adhesive." Current Research, Technology and Education Topics in Applied Microbiology and Microbial Biotechnology. Ed. E. Mendez-Vilas. Badajoz, Spain: Formatex Publishers. In press. (Books and Publications: Forthcoming Publications) 2010

Ramsook, C., C. Tan, M.C. Garcia, R. Fung, G. Soybelman, R. Henry, A. Litewka, S. O'Meally, H.N. Otoo, R.A. Khalaf, A.M. Dranginis, N.K. Gaur, S.A. Klotz, J.M. Rauceo, C.K. Jue and P.N. Lipke. "Yeast Cell Adhesion Molecules Have Functional Amyloid-Forming Sequences." Eukaryotic Cell 9: 393-404. Spotlighted article, ASM Microbe Highlight. (Books and Publications: Peer Reviewed Article) 2010

Thorn, J.L., K.B. Gilchrist, R.E. Sobonya, N.K. Gaur, P.N. Lipke and S.A. Klotz. "Postmortem Candidemia: Contamination or Evidence of Disseminated Disease?" Journal of Clinical Pathology 63: 337-40. (Books and Publications: Peer Reviewed Article) 2010

Xie, X. and P.N. Lipke. "On the Evolution of Yeast and Fungal Cell Walls." Yeast 27: 479-88. (Books and Publications: Peer Reviewed Article) 2010

Alsteens, D., V. Dupres, S.A. Klotz, N.K. Gaur, P.N. Lipke and Y.F. Dufrêne. "Unfolding Individual Als5p Adhesion Proteins on Live Cells." ACS Nano 3: 1677-82. (Books and Publications: Peer Reviewed Article) 2009

Gonzalez, M., P.N. Lipke and R. Ovalle. "GPI Proteins in Biogenesis and Structure of Yeast Cell Walls." The Enzymes Volume 26: Glycosylphophatidylinositol (GPI) Anchoring of Proteins. Eds. Menon, Kinoshita, Orlean and Tamanoi. Academic Press/Elsevier. 321-55. (Books and Publications: Chapter) 2009

Gonzalez, M., P.W.J. de Groot, F.M. Klis and P.N. Lipke. "Glycoconjugate Structure and Function in Fungal Cell Walls." Microbial Glycobiology: Structures, Relevance, and Applications. Eds. A. Moran, P. Brennan, O. Holst and F. von Itzstein. Elsevier. 169-83. (Books and Publications: Chapter) 2009

Thorn, J.L., K.B. Gilchrist, R.E. Sobonya, N.K. Gaur, P.N. Lipke and S.A. Klotz. "Postmortem Candidemia: Contamination or Evidence of Disseminated Disease?" Journal of Clinical Pathology. In press. (Books and Publications: Forthcoming Publications) 2009

Gonzalez, M., P.N. Lipke and R. Ovalle. "GPI Proteins in Biogenesis and Structure of Yeast Cell Walls." The Enzymes Volume 26: Glycosylphophatidylinositol (GPI) Anchoring of Proteins. Eds. Menon, Kinoshita, Orlean and Tamanoi. Academic Press/Elsevier. In press. (Books and Publications: Forthcoming Publications) 2008

Klotz, S.A., N.K. Gaur and P.N. Lipke. "Oropharyngeal Candidiasis: Diagnostic Clues, Treatment Tips." Journal of Respiratory Diseases 29: 128-35. (Books and Publications: Peer Reviewed Article) 2008

Otoo, H.N., K.G. Lee, W.-G. Qiu and P.N. Lipke. "Candida albicans Als Adhesins Have Conserved Amyloid-Forming Sequences." Eukaryotic Cell 7: 776-82. Cover Illustration for Eukaryotic Cell and highlighted in ASM Microbe. (Books and Publications: Peer Reviewed Article) 2008

Spellberg, B. A.S. Ibrahim, L. Lin, V. Avanesian, Y. Fu, P.N. Lipke, H.N. Otoo, T. Ho and J.E. Edwards Jr. "An Antibody Titer Threshold Predicts Anti-Candidal Vaccine Efficacy Even though the Mechanism of Protection Is Induction of Cell-Mediated Immunity" featured article. Journal of Infectious Diseases 197: 967-71. (Books and Publications: Peer Reviewed Article) 2008

Spellberg, B., A.S. Ibrahim, M.R. Yeaman, L. Lin, Y. Fu, V. Avanesian, A.S. Bayer, S.G. Filler, P. Lipke, H. Otoo and J.E. Edwards Jr. "The Anti-Fungal rAls3p-N Vaccine Protects Mice against the Bacterium Staphylococcus aureus." Infection and Immunity 76: 4574-80. (Books and Publications: Peer Reviewed Article) 2008

Coronado, J.E., O. Attie, S.L. Epstein, W.-G Qiu and P.N.Lipke. "Discovery of Recurrent Sequence Motifs in Saccharomyces cerevisiae Cell Wall Proteins." MATCH Communications in Mathematical and in Computer Chemistry 58: 281-99. (Books and Publications: Peer Reviewed Article) 2007

Coronado, J.E., S. Mniemneh, S.L. Epstein, W. Qiu and P.N. Lipke. "Conserved Processes and Lineage-Specific Proteins in Fungal Cell Wall Evolution." Eukaryotic Cell 6: 2269-77. (Books and Publications: Peer Reviewed Article) 2007

Dranginis, A., J.R. Rauceo, J.E. Coronado and P.N. Lipke. "A Biochemical Guide to Yeast Adhesins: Glycoproteins for Social and Antisocial Occasions." Microbiology and Molecular Biology Review 71: 282-94. (Books and Publications: Peer Reviewed Article) 2007

Klotz, S.A., B. Chasin, B. Powell, N.K. Gaur and P.N. Lipke. "Polymicrobial Bloodstream Infections Involving Candida Species: Analysis of Patients and Review of the Literature." Diagnostic Microbiology and Infectious Disease. In press. (Books and Publications: Forthcoming Publications) 2007

Klotz, S.A., N.K. Gaur, R. De Armond, D. Sheppard, N. Khardori, J.E. Edwards Jr., P.N. Lipke and M. El-Azizi. "Candida albicans Als Proteins Mediate Aggregation with Bacteria and Yeasts." Medical Mycology 45: 363-70. (Books and Publications: Peer Reviewed Article) 2007

Coronado, J.E., O. Attie, S.L.Epstein, W.-G Qiu and P.N.Lipke. "Composition-Modified Matrices Improve Identification of Homologs of S. cerevisiae Low-Complexity Gglycoproteins." Eukaryotic Cell 5: 628-37. (Books and Publications: Peer Reviewed Article) 2006

Rauceo, J.M., R. De Armond, H. Otoo, P.C. Kahn, S.A. Klotz, N.K. Gaur and P.N. Lipke. "Threonine-Rich Repeats Increase Fibronectin Binding in the C. albicans Adhesin Als5p." Eukaryotic Cell 5: 1664-73. (Books and Publications: Peer Reviewed Article) 2006

Romov, P.A., F. Li, P.N. Lipke, S.L. Epstein and W.-G. "Comparative Genomics Reveals Long, Evolutionarily Conserved, Low-Complexity Islands in Yeast Proteins." Journal of Molecular Evolution 63: 415-25. (Books and Publications: Peer Reviewed Article) 2006

Kipnis, P., N. Thomas, R. Ovalle and P.N. Lipke. "The v-SNARE Bet1p Is Required for Cell Wall Cross-Linking of S. cerevisiae α-Agglutinin." Microbiology 150: 3219-28. (Books and Publications: Peer Reviewed Article) 2004

Klotz, S.A., N.K. Gaur, D.F. Lake, V. Chan, J. Rauceo and P.N. Lipke. "Degenerate Peptide Recognition by Candida albicans Adhesins Als5p and Als1p." Infection and Immunity 72: 2029-34. (Books and Publications: Peer Reviewed Article) 2004

Klotz, S.A., N.K. Gaur, J. Rauceo, D.F. Lake, Y. Park, K.S. Hahm and P.N. Lipke. "A 23-mer Peptide (Fn/23) With Dual Antifungal Properties: Inhibition of Adherence and Killing of Candida albicans." Antimicrobial Agents Chemotherapy 48: 4337-41. (Books and Publications: Peer Reviewed Article) 2004

Rauceo, J., N.K. Gaur, S.A. Klotz, K.-G. Lee and P.N. Lipke. "Global Cell-Surface Conformational Shift Mediated by a Candida Adhesin." Infection and Immunity 72: 4948-55. (Books and Publications: Peer Reviewed Article) 2004

Creative Work

Cover illustration for Trends in Microbiology, February. Micrograph by Ph.D. mentee Cho Tan, Brooklyn College and the Graduate Center. 2012

Cover illustration for Eukaryotic Cell 9.3; image by collaborator Aaron Frank to accompany Frank et al. 2010

Lipke, P.N., C. Ramsook, C. Tan and S. Klotz. CUNY Patent Application, for "Use of Amyloid Inhibitors to Control Biofilms." 2009

Cover illustration for Eukaryotic Cell 7.5; photo by lab member Henry Otoo accompanying Otoo et al. 2008

Gonzalez, M. and P.N. Lipke. Patent application, for "Screening for Drug Targets and Drugs Affecting Fungal Cell Walls." Filed 2008. 2008

Awards, Honors and Fellowships

NIH R01 098616, for "A Role for Amyloids in Force-Dependent Activation of Cell Adhesion." PI/PD Lipke. 2012-16. (Grants and Fellowships) 2012

Proprietary Strain Production. Biothera, Inc. 2012-13. (Grants and Fellowships) 2012

Biothera, Inc., for "Proprietary Strain Development." (Grants and Fellowships) 2011

NIH Research Grant SC1 GM083756, for "Role of Protein Amyloids in Biofilm Formation." 2008-12. (Grants and Fellowships) 2011

Finalist, NIH Director's Pathfinder Award to increase diversity in science. (Awards and Honors) 2010

National Science Foundation, Acquisition of Surface Plasmon Resonance Spectrometer. 2010-13. (Grants and Fellowships) 2010

NIH Research Grant SC1 GM083756, for "Role of Protein Amyloids in Biofilm Formation." 2008-12. (Grants and Fellowships) 2010

Claire and Leonard Tow Professorship. (Awards and Honors) 2009

NIH Research Grant SC1 GM083756, for "Role of Protein Amyloids in Biofilm Formation." 2008-12. (Grants and Fellowships) 2009

Claire and Leonard Tow Professorship. (Awards and Honors) 2008

NIH Research Grant SC1 GM083756, for "Role of Protein Amyloids in Biofilm Formation." 2008-12. (Grants and Fellowships) 2008

NIH SCORE 1S06 GM 076168, for biomedical research support at Brooklyn College. SCORE project director. 2006-10. (Grants and Fellowships) 2008

Lipke, P. and K.-G. Lee. CUNY Community College Collaborative, for "Cryo-Electron Microscopy of Als Proteins." (Grants and Fellowships) 2007

NIH/NIGMS SCORE Grant, for "Role of Amyloids in Fungal Cell Adhesion." 2004-08. (Grants and Fellowships) 2007

Member fellow, American Association for the Advancement of Science. (Awards and Honors) 2006

Mentoring Award, Hunter College Biology Club. (Awards and Honors) 1998

MARC senior faculty fellow. (Awards and Honors) 1993

Research Activities

Visiting Scientist in Residence, Aberdeen Fungal Group, University of Aberdeen College of Medicine. 2012

Patent application, for "Controlling Biofilms with Amyloid-Inhibiting Treatments." 2009

Conferences, Seminars and Symposiums

"Ale and Alzheimers: Role of amyloids in biofilm formation." Harvard University School of Medicine; University of Massachusetts Boston; University of Aberdeen; Imperial College, London; Brooklyn College; and University of Rochester School of Medicine and Dentistry. (Conferences, Seminars and Symposiums: Invited Talk) 2012

Bois, M., S. Singh, P.N. Lipke and M.C. Garcia. "Friend vs Foe: Functional Amyloid in Commensalism." 4th ASM Conference on Beneficial Microbes. San Antonio. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Garcia, M.C., D. Alsteens, C. Tan, S.A. Klotz, Y.F. Dufrene and P.N. Lipke. "Functional amyloids in C. albicans adhesion." 11th ASM Conference on Candida and candidiasis. San Francisco. (Conferences, Seminars and Symposiums: Invited Talk) 2012

Garcia, M.C., K.B. Gilchrist, A. Filonenko, H. Richards, R. Sobonya, S. Klotz and P. Lipke. "C. albicans cell wall amyloids: A matter of life and death." 11th ASM Conference on Candida and candidiasis. San Francisco. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Garcia, M.C., N. Lysak, S. Singh, R. Sobonya, S.A. Klotz and P.N. Lipke. "A matter of life and death?: Detection of C. albicans cell wall amyloids." 4th ASM Conference on Beneficial Microbes. San Antonio. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Klotz, S.A., M.C. Garcia, R.E. Sobonya and P.N. Lipke. "Biofilm of Candida albicans in Humans. First Demonstration of Fungal Amyloid and Deposition of Serum Amyloid P Component in Invasive Candidiasis." 6th ASM Conference on Biofilms. Miami. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Rameau, Rachele D., Desmond Jackson, Raymond Fung and Peter Lipke. "Investigating ECE1 Function During Hyphae Formation in Candida albicans." ABRCMS 2012. San Jose, Calif. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Samlalsingh, Alyssa, Micheal Bois, Melissa C. Garcia and Peter N. Lipke. "Understanding the Role of Candida Albicans Als5p in C. Elegans Oogenesis." ABRCMS 2012. San Jose, Calif. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

Tan, C., V.G. Gresseau, M.C. Garcia, C. Schloss and P.N. Lipke. "Force-induced activation of amyloid nanodomains of yeast adhesins." 11th ASM Conference on Candida and candidiasis. San Francisco. (Conferences, Seminars and Symposiums: Conference Presentation) 2012

"Ale and Alzheimers: Role of Amyloid in Fungal Cell Adhesion." Department of Biochemistry, University of Washington. (Conferences, Seminars and Symposiums: Invited Talk) 2011

"Cell Adhesion Nanodomains Result From Amyloid Formation on Cell Surfaces." 26th Fungal Genetics Conference. Asilomar, Calif. (Conferences, Seminars and Symposiums: Invited Talk) 2011

"Force-dependent Activation of Functional Amyloid Domains Increases Cell Adhesion in C. albicans." FynSysB conference on Candida. Acquafredda di Maratea, Italy. (Conferences, Seminars and Symposiums: Invited Talk) 2011

"Role of Amyloids in Activation of Fungal Glycoprotein Adhesins." Consortium for Functional Glycomics Meeting. Seattle. (Conferences, Seminars and Symposiums: Invited Talk) 2011

"Sex, Death, Biochemistry, the Social Whirl and Beer: A Role for Amyloids in Fungal Cell Adhesion" seminar. Department of Biochemistry and Microbiology, Rutgers University. (Conferences, Seminars and Symposiums: Invited Talk) 2011

"Candidiasis: Important Clinical and Basic Science Perspectives." Medical Grand Rounds, University of Arizona Health Center. Available at http://streaming.biocom.arizona.edu/event/?id=22794. (Conferences, Seminars and Symposiums: Invited Talk) 2010

"Hydrophobic Aggregation and Functional Amyloids in Cell Adhesion Molecules: Proteins Behaving Badly by Design." Department of Biology Seminar. Syracuse University. April 9. (Conferences, Seminars and Symposiums: Invited Talk) 2010

"The Role of Amyloids in Fungal Cell Adhesion." Joint Biology/Chemistry Seminar. College of Staten Island (CUNY). April 15. (Conferences, Seminars and Symposiums: Invited Talk) 2010

"On the Evolution of Fungal Cell Walls." 5th International Conference on Molecular Mechanisms of Cell Wall Biogenesis. Warsaw, Poland. (Conferences, Seminars and Symposiums: Invited Talk) 2009

"Role of Amyloid Formation in Fungal Cell Adhesion." 5th International Conference on Molecular Mechanisms of Cell Wall Biogenesis. Warsaw, Poland. (Conferences, Seminars and Symposiums: Invited Talk) 2009

"Role of Amyloids in Fungal Cell Adhesion." Benzon Foundation Symposium on Amyloids and Prions. Copenhagen. (Conferences, Seminars and Symposiums: Conference Presentation) 2009

ABRCMS Annual Meeting. Collaborative work presented by Francise Lamothe, Brooklyn College undergraduate. Phoenix. (Conferences, Seminars and Symposiums: Conference Presentation) 2009

Biophysical Society Annual Meeting. Collaborative work presented by Caleen Ramsook, Brooklyn College research associate. (Conferences, Seminars and Symposiums: Conference Presentation) 2009

FASEB Conference on Amyloids. Collaborative work presented by Caleen Ramsook, Brooklyn College research associate. (Conferences, Seminars and Symposiums: Conference Presentation) 2009

Gordon Conference on Proteins. Collaborative work presented by Melissa Garcia, Brooklyn College research associate. (Conferences, Seminars and Symposiums: Conference Presentation) 2009

"How to Write Papers and Get Published in STEM Fields." Mega-Midwest AGEP Conference for Minority Scientists. Chicago. (Conferences, Seminars and Symposiums: Invited Talk) 2008

"Role of Amyloids in Fungal Cell Adhesion." Department of Biology, St. John's University. (Conferences, Seminars and Symposiums: Invited Talk) 2008

"Role of Amyloids in Fungal Cell Adhesion: Proteins Behaving Badly." Department of Biochemistry and Microbiology, Rutgers University. (Conferences, Seminars and Symposiums: Invited Talk) 2008

Wong, K.A., P.N. Lipke, A. Pyronneau and M. Gonzalez. "GFP-GPI Turnover in S. cerevisiae." ABRCMS Conference. Orlando, Fla. (Conferences, Seminars and Symposiums: Conference Presentation) 2008

"Role of Protein Amyloids in Disease." MARC Program, University of Arizona. (Conferences, Seminars and Symposiums: Invited Talk) 2007

Coronado, Juan, Saad Mniemneh, Susan Epstein, WeiGang Qiu and Peter Lipke. "Conserved Processes and Lineage-Specific Components in Fungal Cell Walls." Gordon Conference on Genomics and Evolution. Hinxley, United Kingdom. (Conferences, Seminars and Symposiums: Conference Presentation) 2007

Frank, Aaron, Henry Otoo, Richard De Armond, Nand Gaur, Stephen Klotz and Peter Lipke. "Structure and Function of O-glycosylated Tandem Repeats from Candida Als Proteins." Annual Conference of the Society for Glycobiology. Boston. (Conferences, Seminars and Symposiums: Conference Presentation) 2007

Otoo, Henry, Kyeng Gea Lee and Peter Lipke. "Amyloid Formation in a Fungal Adhesin." Gordon Conference on Proteins (Tilton, N.H.) and American Society for Microbiology Annual Conference (Toronto). (Conferences, Seminars and Symposiums: Conference Presentation) 2007

7th ASM Conference on Candida and Candidiasis. Austin, Texas. (Conferences, Seminars and Symposiums: Invited Talk) 2004

International Meeting on Fungal Cell Walls. Salamanca, Spain. (Conferences, Seminars and Symposiums: Invited Talk) 2003

International Meeting on Fungal Cell Walls. Monte Verita, Switzerland. (Conferences, Seminars and Symposiums: Invited Talk) 2001

Professional Leadership

Grants Workshop, Delaware State University, April 28. (Professional Leadership: Public Service) 2011

Grants workshop, John Jay College (CUNY), March 31. (Professional Leadership: Public Service) 2011

Member, Chancellor's Diversity Study Steering Committee. (Professional Leadership: Committee Service) 2011

Chairman, University of Puerto Rico Medical Science Campus SCORE Program External Advisory Committee. (Professional Leadership: Organizational Leadership Position) 2010

ChairmanOrganism, Biology Department, 2010-13. (Professional Leadership: Organizational Leadership Position) 2010

Co-director, NIH MARC-U*STAR Program, Brooklyn College. (Professional Leadership: Organizational Leadership Position) 2009

Director, NIH NIGMS SCORE Research Program, Brooklyn College. (Professional Leadership: Organizational Leadership Position) 2009

Co-director, MARC Program, Brooklyn College, 2008-10. (Professional Leadership: Organizational Leadership Position) 2008

External Scientific Advisory Committee, NIGMS-SCORE Program, Univeristy of Puerto Rico Medical Science Campus. (Professional Leadership: Committee Service) 2008

Program director, NIGMS SCORE Research Program, Brooklyn College. (Professional Leadership: Organizational Leadership Position) 2007

External advisory committees, St. John's University NIH-Institutional Minority Student Development Program, University of Puerto Rico Medical Sciences Campus NIGMS-SCORE Program, NIH Bridges programs at Borough of Manhattan Community College (CUNY), New York Technical College and CUNY Graduate Center. (Professional Leadership: Committee Service) 2006

Founding project director, MBRS-SCORE Research Program, Hunter College (CUNY), 2000-06. (Professional Leadership: Organizational Leadership Position) 2006

Project director, Brooklyn College MBRS-SCORE Research Program. (Professional Leadership: Organizational Leadership Position) 2006

Project director, MARC Program, Hunter College (CUNY), 1994-2006. (Professional Leadership: Organizational Leadership Position) 2006

Visiting professor, Deptartment of Biochemistry, Cook College, Rutgers University, 1993-present. (Professional Leadership: Organizational Leadership Position) 2004

Member, editorial board, Journal of Bacteriology, 1994-present. (Professional Leadership: Committee Service) 1999

Coordinator, MARC Program, Hunter College (CUNY), 1990-2006. (Professional Leadership: Organizational Leadership Position) 1994

Chairman, CUNY Ph.D. Program in Molecular, Cellular and Developmental Biology, 1991-93. (Professional Leadership: Organizational Leadership Position) 1993

Community Activities

"Yeast Infections, Sherry, Ale and Alzheimer's: The Role of Amyloids in Cell Adhesion." CUNY Science Cafe. April 6. Podcast at http://www1.cuny.edu/portal_ur/news/radio/podcast/lecture_292.mp3. 2010

Tours and demonstrations of research labs for high school students in Brooklyn. 2008

Invited speaker, Science Skills Center High School: World AIDS Day. 2007

Tours and demonstrations of research labs for high school students in Brooklyn. 2007

Other Professional Activities

"Roles of Glycans in Yeast Cell Walls." Glycobiology: The Biomedical & Life Sciences Collection. Ed. M. Pierce. London: Henry Stewart Talks Ltd. Online at http://hstalks.com/?t=BL1483198-Lipke. 2012

ChairmanOrganism, Department of Biology. 2007

Invited speaker on research careers, MARC Program, Queens College (CUNY). 2007

FASEB lecturer. 1996