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Anjana D. Saxena
Associate Professor
Biology
Location: 416 Ingersoll Hall Extension
Phone: 718.951.5000 x2671
Fax: 718.951.4659
Email:
Anjana Saxena studies nucleolar stress factors (NSFs) and their role/s in regulating cell cycle under normal conditions and during cellular responses to DNA damage. Nucleolin is an abundant nucleolar phosphoprotein that is overexpressed in variety of cancers. She studies how nucleolin regulates mRNA stability/translation via direct binding to target-mRNAs or indirectly through protein-protein interactions in the p53 signaling, DNA damage response and ribosomal biogenesis pathways. Her long-term goal is to define the role/s of nucleolin in regulating gene expression that drives cellular decisions of growth (hence, survival and proliferation) or cell cycle arrest (that can lead to repair or cell death) with the potential to identify molecules of therapeutic values.
Education:
Research Assistant Professor, New York University School of Medicine - 2004 (Biochemistry of Tumor Suppressor Pathways)
Postdoctoral Research Scientist, Columbia University - 2000 (Genomic Imprinting, Molecular and Cellular Biology)
Postdoctoral fellow, College of Judea and Samaria (Ariel, Israel) - 1999 (Molecular Genetics)
Ph.D., University of Mumbai (India) - 1997 (Applied Biology (Reproductive Physiology))
M.S., Maharaja Sayajirao University (MSU, Baroda, India) - 1991 (Biochemistry)
B.S., University of Mumbai (India) - 1989 (Microbiology)
Areas of Expertise:
Saxena's lab is actively involved in dissecting growth-promoting and growth-retarding properties of nucleolin by understanding its role in the p14ARF/p53 tumor suppressor network, a key defense against cellular transformation and tumorigenesis.
Books and Publications
"Targeting Piezo1 unleashes innate immunity against cancer and infectious disease"
The CUNY Enhanced Mechanism ENHC-51-122 (Saxena) 07/01/2020-06/30/2021
Talk Title: Fungal complementation in oncogenesis
Editorial Board Member and the News Letter N-Link committee member at AAISCR (American Association of Indian Scientist in Cancer Research), (http://www.aaiscr.org/mission_stat.html), 2016-present. (Professional Leadership: Organizational Leadership Position) 2016
Invited Judge for Quality of Life INNOVATIONS (QLI) Scholars Competition at Working In Support of Education (W!SE) 2014
Invited Reader for the 11th Annual Honors Academy Reading Day, Friday, January 26, 2018.
Aykut B, Chen, R., Kim, J. I., Wu, D., Shadaloey, S.A., Abengozar, R., Preiss, P., Saxena, A., Pushalkar, S., Leinwand, J., and Diskin B, Wang, W., Werba, G. Berman, M., Khodadadi-Jamayran, A., Saxena, D., Coetzee, W.A., and Miller, G.
August 2020, Science Immunology 5(50)
DOI: 10.1126/sciimmunol.abb5168 (Books and Publications: Article (Peer-reviewed)) 2020
Nucleolin regulates 14-3-3zeta mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation
Sunayana Dagar, Pushpa Kumari, Diksha Pathak, Sarbani Samaddar, Anjana Saxena, Sourav Banerjee and Sivaram V S Mylavarapu*.
FASEB November 2020, Accepted.
(Books and Publications: Article (Peer-reviewed)) 2020
Prenatal Choline Supplementation during High-Fat Feeding Improves Long-Term Blood Glucose Control in Male Mouse Offspring.
Korsmo HW, Edwards K, Dave B, Jack-Roberts C, Yu H, Saxena A, Salvador M, Dembitzer M, Phagoora J5, Jiang X.
Nutrients. 2020 Jan 4;12(1). pii: E144. doi: 10.3390/nu12010144. (Books and Publications: Article (Peer-reviewed)) 2020
"The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL"
Berk Aykut, Smruti Pushalkar, Ruonan Chen, Qianhao Li, Raquel Abengozar, Jacqueline I. Kim, Sorin A. Shadaloey, Dongling Wu, Pamela Preiss, Narendra Verma, Yuqi Guo, Anjana Saxena, Mridula Vardhan, Brian Diskin, Wei Wang, Joshua Leinwand, Emma Kurz, Juan A. Kochen Rossi, Mautin Hundeyin, Constantinos Zambrinis, Xin Li, Deepak Saxena & George Miller.
Nature Oct. 2, (2019), DOI:10.1038/s41586-019-1608-2; 1.
https://rdcu.be/bSQ4t (Books and Publications: Article (Peer-reviewed)) 2019
Nanobashvili K, Jack-Roberts C, Bretter R, Jones N, Axen K, et al. Maternal Choline and Betaine Supplementation Modifies the Placental Response to Hyperglycemia in Mice and Human Trophoblasts. Nutrients 2018 Oct 15; 10(10). PMID: 30326592; PMCID: PMC6213524. (Books and Publications: Article (Peer-reviewed)) 2018
Smruti Pushalkar, Mautin Hundeyin, Donnele Daley, Constantinos P. Zambirinis, Emma Kurz, Ankita Mishra, Navyatha Mohan, Berk Aykut, Mykhaylo Usyk, Luisana E. Torres, Gregor Werba, Kevin Zhang, Yuqi Guo, Qianhao Li, Neha Akkad, Sarah Lall, Benjamin Wadowski, Johana Gutierrez, Juan Andres Kochen Rossi, Jeremy W. Herzog, Brian Diskin, Alejandro Torres-Hernandez, Josh Leinwand, Wei Wang, Pardeep S. Taunk, Shivraj Savadkar, Malvin Janal, Anjana Saxena, Xin Li, Deirdre Cohen, R. Balfour Sartor, Deepak Saxena, George Miller.
"The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression"
Cancer Discovery, Apr;8(4):403-416, 2018. PMID:29567829
doi: 10.1158/2159-8290.CD-17-1134. 2018.
(Books and Publications: Article (Peer-reviewed)) 2018
Yaelle Joselit, Khatia Nanobashvili, Chauntelle Jack-Roberts, Esther Greenwald, Olga V Malysheva, Marie A Caudill, Anjana Saxena, Xinyin Jiang
Maternal betaine supplementation affects fetal growth and lipid metabolism of high-fat fed mice in a temporal-specific manner
Nutr Diabetes. 2018 May 24;8(1):41. doi: 10.1038/s41387-018-0035-z. PMID:30026535
PMCID:PMC6053452
(Books and Publications: Article (Peer-reviewed)) 2018
Jack-Roberts C, Joselit Y, Nanobashvili K, Bretter R, Malysheva OV, Caudill MA, Saxena A, Axen K, Gomaa A, Jiang X.
"Choline Supplementation Normalizes Fetal Adiposity and Reduces Lipogenic Gene Expression in a Mouse Model of Maternal Obesity."
Nutrients. 2017 Aug 18;9(8). pii: E899. doi: 10.3390/nu9080899. (PMCID:PMC5579692) (Books and Publications: Article (Peer-reviewed)) 2017
Nam J, Greenwald E, Jack-Roberts C, Ajeeb TT, Malysheva OV, Caudill MA, Axen K, Saxena A, Semernina E, Nanobashvili K, Jiang X. "Choline prevents fetal overgrowth and normalizes placental fatty acid and glucose metabolism in a mouse model of maternal obesity."
J Nutr Biochem. 2017 Aug 12;49:80-88. doi: 10.1016/j.jnutbio.2017.08.004. [Epub ahead of print]
PMID:28915389 DOI:10.1016/j.jnutbio.2017.08.004 (Books and Publications: Article (Peer-reviewed)) 2017
Zhang, X., Xiao, S., Rameau, R., Devany, E., Nadeem, Z. Caglar, E., Ng, K.,Kleiman, F. and *Saxena, A. Nucleolin phosphorylation regulates PARN deadenylase activity during cellular DNA damage response. (*Saxena-Corresponding author, Xiao, S-PhD student, Ms. Nadeem and Ms. Caglar completed MA, Biology, 2012; Collaborator at Hunter College: Dr. Kleiman and Zhang/Devany PhD students.
RNA Biol. 2017 Nov 23:0. doi: 10.1080/15476286.2017.1408764. [Epub ahead of print]
[CA175794 & PSC-CUNY Awards # Award # 66740-00 44, CIRG #80209-07 19] (Books and Publications: Article (Peer-reviewed)) 2017
Fleisher KE, Vyas S, Li X, Saxena A, Glickman RS, Phelan JA, Saxena, D. "Update on the Pathogenesis of Medication-Related Osteonecrosis of the Jaw: The Perfect Storm." In Marx Festschrift Textbook: Hanover Park, Illinois: Quintessence Publishing Company. 2016. (Books and Publications: Book Chapter) 2016
Min Dai, Frezzo JA, Sharma E, Chen R, Singh N, Yuvienco C, *Caglar E, *#Xiao S, 2Saxena A and Montclare JK. "Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials for Small Molecule Delivery." J Nanomed Nanotechnol Volume 7, Issue 1, 1000356, 2016. (*Caglar E, MA and *# Xiao S, PhD students in *Saxena lab), 2016 (http://dx.doi.org/10.4172/2157-7439.1000356) (Books and Publications: Article (Peer-reviewed)) 2016
Xiao, Shu, Elif Caglar, Priscilla Maldonado, Dibash Das, Zaineb Nadeem, Angela Chi, Benjamin Trinité, Xin Li and Anjana Saxena. "Induced expression of nucleolin phosphorylation-deficient mutant confers dominant-negative effect on cell proliferation." PLOS ONE. DOI: 10.1371/journal.pone.0109858
PMID: 25313645. PMCID:PMC4196967.
[CA175794 & PSC-CUNY Awards # 60040-39 40, #80209-07 19] (Books and Publications: Article (Peer-reviewed)) 2014
Akinyeke, T., S. Matsumura, X. Wang, Y. Wu, E.D. Schalfer, A. Saxena, W. Yan, S.K. Logan and X. Li.
"Metformin Targets c-MYC Oncogene to Prevent Prostate Cancer." Carcinogenesis 34.12: 2823-32. (PMID: 24130167). (Books and Publications: Article (Peer-reviewed)) 2013
Bhatt, Purvi, Claire d'Avout, Naomi S. Kane, James A. Borowiec and Anjana Saxena (corresponding author). "Specific Domains of Nucleolin Interact With Hdm2 and Antagonize Hdm2-mediated p53-ubiquitination." FEBS Journal 279: 370-83 (PMID: 22103682). (Books and Publications: Article (Peer-reviewed)) 2012
"DNA Repair" Gallus Reactome: http://www.reactome.org/PathwayBrowser/#SPECIES=49591&DIAGRAM=353377&PATH=1670466. (Books and Publications: Article (Peer-reviewed)) 2009
Saxena, A., C. Rorie, Dimitrova, Y. Daniely and J. Borowiec. "Nucleolin Inhibits Hdm2 by Multiple Pathways Leading to p53 Stabilization." Oncogene 25: 7274-88. http://www.ncbi.nlm.nih.gov/pubmed/15743838 (Books and Publications: Article (Peer-reviewed)) 2006
Kim, K., D.D. Dimitrova, K.M. Carta, A. Saxena, M. Daras and J.A. Borowiec. "Novel Checkpoint Response to Genotoxic Stress Mediated by Nucleolin-replication Protein a Complex Formation." Molecular Cell Biology 25: 2463-74. http://www.ncbi.nlm.nih.
Bhatt, P., K. Kadam, A. Saxena and U. Natraj. "Fertilization, Embryonic Development and Oviductal Environment: Role of Estrogen Induced Oviductal Glycoprotein." Indian Journal of Experimental Biology 42, November: 1043-55. http://www.ncbi.
Salas, M., R. John, A. Saxena, S. Barton, D. Frank, G. Fitzpatrick, M.J. Higgins and B. Tycko. "Placental Growth Retardation Due to Loss of Imprinting of Phlda2." Mechanisms of Development 121: 1199-1210. http://www.ncbi.nlm.nih.gov/
Tycko, B., J.H. Lee, A. Ciappa, A. Saxena, C.M. Li, L. Feng, A. Arriaga, Y. Stern, R. Lantigua, N. Shachter and R. Mayeux. "APOE and APOC1 Promoter Polymorphisms and the Risk of Alzheimer Disease in African American and Caribbean Hispanic Individuals." Archives of Neurology 61: 1434-39. http://www.ncbi.nlm.nih.gov/
Saxena, A., D. Frank, B. Tycko and H. Thakkar. "The Product of the Imprinted Gene Ipl Marks Human Villous Cytotrophoblast and Is Lost in Hydatidiform Mole." Placenta 24: 835-42. http://www.ncbi.nlm.nih.gov/pubmed/13129680 (Books and Publications: Article (Peer-reviewed)) 2003
Frank, D., W. Fortino, L. Clark, R. Musalo, W. Wang, A. Saxena, C.M. Li, T. Ludwig, W. Reik and B. Tycko. "Placental Overgrowth in Mice Lacking the Imprinted Gene Ipl." Proceedings of the Natinoal Academy of Science (USA) 99: 7490-95. http://www.ncbi.nlm.nih.gov/pubmed/12032310 (Books and Publications: Article (Peer-reviewed)) 2002
Ottaviani, E., A. Franchini, M. Mandrioli, A. Saxena, A. Hanukoglu and I. Hanukoglu. "Amiloride-sensitive Epithelial Sodium Channel (ENaC) Subunits Are Expressed in Human and Mussel Immunocytes." Development & Comparative Immunology 26: 395-402. http://www.ncbi.nlm.nih.gov/pubmed/11906720 (Books and Publications: Article (Peer-reviewed)) 2002
Saxena, A., I. Hanukoglu, D. Saxena, R.J. Thompson, R.M. Gardiner and A. Hanukoglu. "Novel Mutations in Amiloride-Sensitive Epithelial Sodium Channel Subunits Responsible for Multi-System Pseudohypoaldosteronism." Journal of Clinical Endocrinology & Metabolism 87: 3344-50. http://www.ncbi.nlm.nih.gov/pubmed/11906720 (Books and Publications: Article (Peer-reviewed)) 2002
Saxena, A., P. Morozov, D. Frank, R. Musalo, M.A. Lemmon, E.Y. Skolnik and B. Tycko. "Phosphoinositide Binding by the Pleckstrin Homology Domains of Ipl and Tih1." Journal of Biological Chemistry 277: 49935-44. http://www.ncbi.nlm.nih.gov/
Hanukoglu, A., A. Saxena and I. Hanukoglu. "Aldosterone Insensitivity Syndromes
(Pseudohypoaldosteronism): From Clinic to Molecular Biology of Sodium Transport." Polish Journal of Endocrinology 52: 27-37. (Books and Publications: Article (Peer-reviewed)) 2001
Hanukoglu, A., A. Saxena, R.M. Gardiner and I. Hanukoglu. "Aldosterone Unresponsiveness (Pseudohypoaldosteronism) Results From Mutations in Epithelial Sodium Channel Subunits. Molecular Steroidogenesis. Eds. M. Okamoto, Y. Ishimura and H. Nawata. Tokyo: Universal Academy Press. 369-70. (Books and Publications: Article (Other)) 2000
Shah, A., T.D. Nandedkar, V.P. Raghavan, S.V. Parulekar and U. Natraj. "Characterization and Localization of Estrogen and Progesterone Receptors of the Human Fallopian Tube." Indian Journal of Experimental Biology 37: 893-99. http://www.ncbi.nlm.nih.gov/pubmed/10687285 (Books and Publications: Article (Peer-reviewed)) 1999
Saxena, A., I. Hanukoglu, S.S. Strautnieks, R.J. Thompson, R.M. Gardiner and A. Hanukoglu. "Gene Structure of the Human Amiloride-sensitive Epithelial Sodium Channel Beta Subunit." Biochemical and Biophysical Research Communications 252: 208-13. http://www.ncbi.nlm.nih.gov/pubmed/9813171 (Books and Publications: Article (Peer-reviewed)) 1998
Shah, A., S. Kundale, V.P. Raghavan, T.D. Nandedkar, I. Hinduja, S.V. Parulekar and U. Natraj. "Effect of Estrogen and Progesterone on Newly Synthesized and Released Human Fallopian Tube Specific Proteins." Indian Journal of Experimental Biology 36: 564-68. http://www.ncbi.nlm.nih.gov/pubmed/9731469 (Books and Publications: Article (Peer-reviewed)) 1998
Awards, Honors and Fellowships
Title: Fungal dysbiosis activate pattern recognition receptors pathways and cause immune suppression to promote pancreatic ductal carcinoma (PDA)
(Grants and Fellowships) 2020
Title: Succinate triggers gut dysbiosis and activates SUCNR1 to enhance inflammaging
NIH (NIA); #1R01AG068857-01; Role: co-I
Lead PI: Xin Li (NYU College of Dentistry)
08/15/2020 - 04/30/2025 (Grants and Fellowships) 2020
AACR Minority-Serving Institution (MSI) Faculty Scholar Award in Cancer Research, for participation in the AACR Annual Meeting, Washington D.C. April 1-5th, 2017 (Awards and Honors) 2017
CUNY Interdisciplinary Research Grant (IRG) Program, "The role of choline in reducing perinatal stress and improving birth outcomes of gestational diabetes in a high-risk urban population" July1, 2017 - June 30, 2019.
Participating PI: Xinyin Jiang (Health & Nutrition) and Anjana Saxena (Brooklyn College) .
July, 2017- June, 2019.
(Grants and Fellowships) 2017
Student Technology Fee (STF) to purchase an Odyssey Fc DNA and protein imager for lab courses and student research, Brooklyn College;
Multi-PI: Dr. Xinyin Jiang (Nutrition Dept.) and Dr. Saxena (Biology) (Grants and Fellowships) 2017
Sackler Institute for Nutrition Research Grant Oct. 2016-Oct. 2019
"Prenatal betaine supplementation as a treatment for macrosomia in a mouse model of gestational diabetes mellitus"
Funding Agency: The New York Academy of Sciences
Multi-PI: Dr. Xinyin Jiang (Nutrition Dept.) and Dr. Saxena (co-PI)
(Grants and Fellowships) 2016
Awarded Cancer Disparity Research Network Travel Grant to present posters at AACR Annual meeting at Pennsylvania Convention Center, Philadelphia, Pennsylvania, April 18-22, 2015 (Awards and Honors) 2015
Student Technology Fee (STF), to purchase Cellometer K2 Image Cytometer (Nexcelom Biosciences), June. (Grants and Fellowships) 2014
AACR Minority-Serving Institution (MSI) Faculty Scholar Award in Cancer Research, for participation in the AACR 104th Annual Meeting, Washington, D.C., April 6-10. (Awards and Honors) 2013
NIH Exploratory/Developmental Research Grant Award (R21) from NCI, for "Role of Nucleolin in Regulating mRNA Stability During DNA Damage Response (DDR)." Multi-PI award: Frida Kleiman(Chemistry Department, Hunter College) and Anjana Saxena (Biology Department, Brooklyn College). 2013-15. (Grants and Fellowships) 2013
PSC-CUNY Award, for "To Evaluate Nucleolin Phosphorylation by CK2 During Normal Cell Cycle and Upon DNA Damage." (Grants and Fellowships) 2013
The CUNY Collaborative Incentive Research Grant (CIRG) Program, for "Role of Nucleolin in Regulating mRNA Stability During DNA Damage Response." Participating PI: Anjana Saxena (Brooklyn College) and Frida Kleiman (Hunter College). 2012-13. (Grants and Fellowships) 2012
AACR Minority-Serving Institution (MSI) Faculty Scholar Award in Cancer Research, for participation in the AACR 102nd Annual Meeting, Orlando, Fla., April 2-7. (Awards and Honors) 2011
New Faculty Fund (Brooklyn College), for "Nucleolin Phosphorylation by CK2 Modulates B23-ARF Interaction." (Grants and Fellowships) 2011
Awarded to participate at University of Kentucky/National Institute of General Medical Sciences Internet Grant Writing Program, University of Kentucky, May 10-12. (Awards and Honors) 2010
New Faculty Fund (Brooklyn College), for "Phosphorylation of Nucleolin Alters Nucleolin-B23 Interaction." (Grants and Fellowships) 2010
PSC-CUNY Award, for "Disruption of Nucleolin-Hdm2 Interaction Is Dependent on Nucleolin Phosphorylation." (Grants and Fellowships) 2010
New Faculty Fund (Brooklyn College), for "Nucleolin Regulates Subnuclear Localization of Nucleophosmin." (Grants and Fellowships) 2009
PSC-CUNY Award, for "Nucleolin Inhibits ARF Tumor Suppressor Protein." (Grants and Fellowships) 2009
Conferences, Seminars and Symposiums
NYC Yeast Club Meeting, CUNY Graduate Center, Wednesday, January 22, 2020
(Conferences, Seminars and Symposiums: Invited Talk) 2020
Poster: The Fungal Mycobiome Promotes Pancreatic Oncogenesis via MBL Activation
Berk Aykut, Ruonan Chen, Smruti Pushalkar, Qianhao Li, Raquel Abengozar, Dongling Wu, Pamela Preiss, Narendra Verma, Yuqi Guo, Anjana Saxena, Brian Diskin, Sorin A. Shadaloey, Jacqueline I. Kim, Joshua Leinwand, Emma Kurz, Juan A. Kochen Rossi, Xin Li, Deepak Saxena#, George Miller#
Immunology & Inflammation Program Meeting, NYU Langone Medical Center, June 19, 2019
(Conferences, Seminars and Symposiums: Conference Presentation) 2019
Talk Title: "Stressed out" nucleolar proteins: Nucleolin (NCL) phosphorylation in
RNA binding and gene expression.
ASBMB Special Symposium Emerging Roles for the Nucleolus,
Organizers:Drs. Jennifer Gerton, Francesca Duncan and Craig Pikaard.
Stowers University in Kansas City, MO, October 24 - 27, 2019. (Conferences, Seminars and Symposiums: Invited Talk) 2019
Invited Talk: "RNA control by RNA Binding Domains: Nucleolar Story"
Special session: RNA at MCD/Neurobiology PhD Program retreat at Pocono Environmental Education Center (PEEC), PA, Sept. 14-16, 2018. (Conferences, Seminars and Symposiums: Invited Talk) 2018
Poster: Valerio Embrione, Michael Scarpati, Zachary D. Uzzel, Rahimah Ahmad, Fortuna A. De Sury, Tyler J. Sheetz, Vincenzo Coppola, Shaneen M. Singh, Anjana D. Saxena, Carlo M. Croce, Dario Palmieri. "A human scFv as a tool to understand the biogenesis of a subset of oncogenic microRNAs" Category: Accepted poster as late breaking/clinical, Abstract # 476 American Association for Cancer Research Annual Meeting Proceedings, McCormick Place North/South Chicago, Illinois, April 14-15, 2018.
(Collaborative project with Dr. Palmieri at OHU)
(Conferences, Seminars and Symposiums: Conference Presentation) 2018
Talk: "Nucleolar control of gene expression in DNA damage response" at Cancer Research at Brooklyn College and Partnerships with MSKCC and the CUNY-ASRC, Brooklyn College, June 7th, 2018. (Actively contributed in organizing this event) (Conferences, Seminars and Symposiums: Invited Talk) 2018
Invited Talk: "Hit Cancer Cells at the Central Command: Nucleolar control of gene expression", at
SVKM's NMIMS, Sunandan Divatia School of Science, Mumbai, India, July, 19th 2017. (Conferences, Seminars and Symposiums: Invited Talk) 2017
Invited Talk at Bronx Community College, Celebrating 60 years in STEM Program, Nov. 9, 2017, Bronx, NY. (Conferences, Seminars and Symposiums: Invited Talk) 2017
Poster: *Iqra Nadeem, $Amna Aslam, #Jingyuan Wang, *Anna Kozlova, *Danielle Gordon, $Rumsha Javed, *Ruchama Steinberg, 1, @Rachele Dolce Rameau, Xinyin Jiang and Anjana Saxena "Higher nucleolar index of nucleolin as an indicator of aberrant cellular DNA damage response (DDR)" Category: MCB/Genetics (Molecular Carcinogenesis and Chromosomal Alternations), Abstract # 3150, American Association for Cancer Research Annual Meeting Proceedings, Washington D.C., April 1-5, 2017. ($HS, *UG,@PhD students). (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Poster: *Kamrun Begum, *Ruchama Chaya Steinberg, Anjana Saxena and Shaneen Singh "Delineating the role of multiple copies of RNA binding domains in human nucleolin and its homologs using a computational approach" Category:Bioinformatics and Systems Biology, Abstract # 1553, American Association for Cancer Research Annual Meeting Proceedings, Washington D.C., April 1-5, 2017. (*UG students). (Conferences, Seminars and Symposiums: Conference Presentation) 2017
Invited Talk: "Cellular Response to DNA Damage: a Nucleolar Story", at National Institute for Research in Reproduction, India, July31th, 2015. (Conferences, Seminars and Symposiums: Invited Talk) 2015
Poster: Esther Akinwunmi, Shu Xiao, Yuqi Guo, Xin Li and *Anjana Saxena. "Nucleolin phosphorylation by CK2 is important for its role in regulating apoptosis." Category: MCB (Cell Death Mechanisms), Abstract # 14, American Association for Cancer Research 106th Annual Meeting Proceedings, Philadelphia, PA, April 18-22, 2015. (The graduating minority MA student, Ms.. Akinwunmi presented her thesis research as a poster presentation). (Conferences, Seminars and Symposiums: Conference Presentation) 2015
Poster: Ruchama Chaya Steinberg, Shaneen Singh and *Anjana Saxena. "Dissecting the potential distinct role/s of the four RNA binding domains in a phosphoprotein nucleolin using bioinformatics tool." Category: MCB (Examination of Cancer Pathways Using Computational Approaches), Abstract # 1089, American Association for Cancer Research 106th Annual Meeting Proceedings, Philadelphia, PA, April 18-22, 2015. (Conferences, Seminars and Symposiums: Conference Presentation) 2015
Invited Talk: "Got Stress? Cellular Options: 'Survive or Die.'" Brooklyn College Science Retreat. May 16. (Conferences, Seminars and Symposiums: Invited Talk) 2014
Invited Talk: "Hit Cancer Cells at the Central Command: Nucleolar control of gene expression", at Brooklyn College American Medical Student Association Oct 16th, 2014. (Conferences, Seminars and Symposiums: Invited Talk) 2014
Invited Talk: "How Nucleolar Stress Factors Regulate Cellular Decision of Survival or Death." Biological Sciences Department, Lehman College (CUNY), May 5. (Conferences, Seminars and Symposiums: Invited Talk) 2014
Invited Talk: "Nucleolin Phosphorylation: A 'Molecular Switch' to Regulate Gene Expression." Chemistry Department, Lehman College (CUNY). New York, April 2. (Conferences, Seminars and Symposiums: Invited Talk) 2014
Poster: Ng, K., A. Rodriguez and A. Saxena. "Nucleolin phosphorylation profiling under normal and cellular stress conditions." Category: MCB64 Cell Cycle2. Abstract #5093, American Association for Cancer Research 105th Annual Meeting Proceedings, San Diego, April 5-9. (Conferences, Seminars and Symposiums: Conference Presentation) 2014
Poster: Zhang, Xiaokan, Shu Xiao, Emral Devany, Zaineb Nadeem, Elif Caglar ýþýn, Frida Kleiman and Anjana D. Saxena. "Nucleolin Phosphorylation Mediated Regulation of Gene Expression in Determining Cellular Fate During the DNA Damage Response (DDR)." Category: MCB05-09 Posttranscriptional and translational control. Abstract #3188, American Association for Cancer Research 104th Annual Meeting Proceedings, Washington, D.C., April 6-10. (Conferences, Seminars and Symposiums: Conference Presentation) 2013
"Metformin Targets Tumor Cells and the Microenvironment to Prevent Prostate Cancer Initiation and Growth in Bone." Tunde Akinyeke, New York University; Xinying Wang, New York University; Satoko Matsumura, New York University; Himaly Shinglot, New York University; Rupak Bhatt, New York University; Anjana Saxena, Brooklyn College; Wenbo Yan, Nyack College; Xin Li, New York University. Oral Presentations, Presentation Number 1087. Concurrent Oral Session 15: Greg Mundy Memorial Cancer and Bone Session ASBMR annual meeting, Minneapolis, Oct. 12-15. (Conferences, Seminars and Symposiums: Contributed Talk) 2012
Invited Talk: "Role of Nucleolin Phosphorylation and Regulation of Cell Cycle." Biology Department, Queen's College. May 18. (Conferences, Seminars and Symposiums: Invited Talk) 2011
Poster: Caglar, E., D. Das, J. Borowiec and A. Saxena. "Nucleolin Phosphorylation by CK2 Modulates Its Role in Cell Cycle Checkpoint Activation, Category: Cellular and Molecular Biology." Abstract #2967, American Association for Cancer Research 102nd Annual Meeting Proceedings, April 2-6. (Conferences, Seminars and Symposiums: Conference Presentation) 2011
Invited Talk: "Nucleolar Stress: Role of Nucleolin in Tumor Suppression." Biology Department, Long Island University, Brooklyn campus, Feb. 22. (Conferences, Seminars and Symposiums: Invited Talk) 2010
Poster: Bhatt, P., C. d'Avout, N. Kane, J. Borowiec and A. Saxena. "Nucleolin Inhibits Hdm2-mediated p53 Ubiquitination Using Multiple Interactions, Category: Tumor Metabolism and Regulation of Apoptosis." Abstract #4532, American Association for Cancer Research 101st Annual Meeting Proceedings, April 17-21. (Conferences, Seminars and Symposiums: Conference Presentation) 2010
Invited Talk: Saxena, A., C. Rorie, Dimitrova, Y. Daniely and J. Borowiec. "Nucleolin Inhibits Hdm2 by Multiple Pathways Leading to p53 Stabilization." 12th Virus-Host Interactions Symposium. New York Academy of Sciences. New York. (Conferences, Seminars and Symposiums: Invited Talk) 2006
Invited Talk: Saxena, A., D. Frank and B. Tycko. "Properties of the PH-domain Proteins Encoded by the Imprinted Gene Ipl and Its Relative Tih1" workshop. 3rd Annual Conference on Sex and Gene Expression. Society for Women's Health Research. San Jose, Calif. (Conferences, Seminars and Symposiums: Invited Talk) 2002
Invited talk: Saxena, A., I. Hanukoglu, S.S. Strautnieks, et al. "Elucidation of the Gene Structure of the Epithelial Sodium Channel Beta Subunit Reveals a New Mutation That Causes Unresponsiveness to Aldosterone." Israel Endocrine Society. Tel-Aviv, Israel. (Conferences, Seminars and Symposiums: Invited Talk) 1999
Invited Talk: Shah, A., V.P. Raghavan, S.B. Moodbidri, et al. "Hormonal Regulation of the Secreted Proteins of the Human Fallopian Tube in-vitro." IXth World Congress on Human Reproduction and Vth Conference on Fallopian Tube in Health and Disease. WCHR. Philadelphia. (Conferences, Seminars and Symposiums: Invited Talk) 1996
Professional Leadership
Faculty Member, Faculty Council Committee on Undergraduate Curriculum and Degree Requirement (CUDR): 2014-2017 (Professional Leadership: Committee Service) 2014
Faculty Member, School-wide strategic planning committee: 2014-2015 (Professional Leadership: Committee Service) 2014
Member, CUNY Collaborative Incentive Research Grant (CIRG) Review Oversight Committee, 2014-15. (Professional Leadership: Committee Service) 2014
Member, Student Tech Fee Committee, 2012-14. (Professional Leadership: Committee Service) 2012
Member, AACR special program for high school and undergraduate mentoring, 2011-present. (Professional Leadership: Public Service) 2011
CUET (Computer Utilization and Educational technology) committee member, 2010-11, 2013-14. (Professional Leadership: Committee Service) 2010
Member, Biochemistry Doctoral Recruitment and Curriculum Development Committee, 2010-present. (Professional Leadership: Committee Service) 2010
Faculty Council Committee member for Library, 2009-10. (Professional Leadership: Committee Service) 2009
Science divisional alternate for Faculty Council, 2009-10, 2011-12. (Professional Leadership: Committee Service) 2009
Community Activities
Invited Judge for Quality of Life INNOVATIONS (QLI) Scholars Competition at Working In Support of Education (W!SE) 2012
Member, Working In Support of Education (W!SE), 2012-present. 2012
Invited Judge: Rohm and Hass Middle School Science exhibition, Long Island 2008
Invited Judge: Rohm and Hass Middle School Science exhibition, Long Island 2004
Other Professional Activities
Readers evaluate admissions applications for the college's four freshmen admitting honors programs: B.A.-M.D, Honors Engineering, Macaulay Honors College, and, The Scholars Program to select the Honors Academy Class of 2022.
2017
Invited Reviewer for Cancer Research Fellowship applications from New Jersey Commission on Cancer Research (NJCCR) - State of New Jersey. 2017
Editorial Board Member of the News Letter committee at AAISCR (American Association of Indian Scientist in Cancer Research), 2016-present. 2016
Faculty Day Panel Organizer, Presenter and Moderator: "Cancer Crossroads: Prevention, Progression, and Precision Medicine", May 2016. 2016
Invited Judge for NYCSeF, City College 2016
Invited member in judging the CUNY Nobel Essay Challenge-Chemistry Nobel Prize, February 2016 2016
Invited Reviewer for Cancer Research Fellowship applications from New Jersey Commission on Cancer Research (NJCCR) - State of New Jersey. 2016
Invited Panelist: "HeLa's Troubled Legacy: Multidisciplinary Perspectives on The Immortal Life of Henrietta Lacks" faculty panel discussion. Wolfe Institute for the Humanities in collaboration with the First College Year Program. Brooklyn College, Nov. 6. 2012
Active Member of American Association for Cancer Research: 2010-present 2010
Patent US20040248190: ?Compositions and kits for differential diagnosis of hydatidiform moles and methods of using the same?. Tycko B., Thaker H. and Saxena, A. 2004
