- Home
- Academics
- Schools
- School of Natural and Behavioral Sciences
- Undergraduate Departments
- Biology
- Faculty
- Detailed Information
Luis E. N. Quadri
Professor
Biology
Location: 323 Ingersoll Hall Extension
Phone: 718.951.5000 x6254
Fax: 718.951.4659
Email:
Before joining Brooklyn College as Carol and Larry Zicklin Professor in Biology in January 2010, Luis Quadri held faculty and head of laboratory/principal investigator positions at Weill Medical College of Cornell University for 10 years.
Education:
Postdoctoral Training, Harvard Medical School - 1999 (Biochemistry)
Ph.D., University of Alberta (Canada) - 1996 (Microbiology)
B.S.-Licenciature, University of Buenos Aires (Argentina) - 1990 (Biology)
Areas of Expertise:
Luis Quadri's lab applies multidisciplinary approaches to: (1) investigate the biosynthesis of mycobacterial iron-chelating compounds utilized for iron uptake (siderophores); (2) elucidate the biosynthesis of lipidic mycobacterial virulence factors called DIMs; and (3) develop compounds with utility as leads for drug development or chemical biology tools.
Books and Publications
Chavadi, Onwueme, Edupuganti, Jerome, Chatterjee, Soll and Quadri. "The Mycobacterial Acyltransferase PapA5 Is Required for Biosynthesis of Cell Wall-associated Phenolic Glycolipids." Microbiology 158:1379-1387. http://mic.sgmjournals.org/content/158/Pt_5/1379.full.pdf+html (Books and Publications: Peer Reviewed Article) 2012
Tatham, Chavadi, Mohandas, Edupuganti, Angala, Chatterjee and Quadri. "Production of Mycobacterial Cell Wall Glycopeptidolipids Requires a Member of the MbtH-like Protein Family." BMC Microbiology 12:118 http://www.biomedcentral.com/content/pdf/1471-2180-12-118.pdf (Books and Publications: Peer Reviewed Article) 2012
Chavadi, Edupuganti, Vergnolle, Fatima, Singh, Soll and Quadri. "Inactivation of tesA Reduces Cell-Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria." Journal of Biological Chemistry 286: 24616-25. http://www.ncbi.nlm.nih.gov/pubmed?term=21592957 (Books and Publications: Peer Reviewed Article) 2011
Chavadi, Stirrett, Edupuganti, Vergnolle, Sadhanandan, Marchiano, Martin, Qiu, Soll and Quadri. "Mutational and Phylogenetic Analyses of the Mycobacterial mbt gene cluster." Journal of Bacteriology 193: 5905-13. http://jb.asm.org/cgi/content/abstract/JB.05811-11v1. In press. (Books and Publications: Forthcoming Publications) 2011
Ferreras, Gupta, Amin, Basu, Sinha, Worgall, Jayapraksh and Quadri. "Chemical Scaffolds With Structural Similarities to Siderophores of Nonribosomal Peptide-polyketide Origin as Novel Antimicrobials Against Mycobacterium tuberculosis and Yersinia pestis". Bioorganic & Medicinal Chemistry Letters 21: 6533-37. http://www.sciencedirect.com/science/article/pii/S0960894X11011474. (Books and Publications: Forthcoming Publications) 2011
He, Soll, Chavadi, Zhang, Warren and Quadri. "Cooperation Between a Coenzyme A-Independent Stand-Alone Initiation Module and an Iterative Type I Polyketide Synthase During Synthesis of Mycobacterial Phenolic Glycolipids." Journal of the American Chemical Society 131: 16744-50. http://www.ncbi.nlm.nih.gov/pubmed?term=19799378. (Books and Publications: Peer Reviewed Article) 2009
Xu, Tertilt, Krause, Quadri, Crystal and Worgall. "Influence of the Cystic Fibrosis Transmembrane Conductance Regulator on Expression of Lipid Metabolism-related Genes in Dendritic Cells." Respiratory Research 10: 26. (Flagged as "Highly Accessed" by Respiratory Research.) http://www.ncbi.nlm.nih.gov/pubmed?term=19344509. (Books and Publications: Peer Reviewed Article) 2009
"Iron Uptake by Mycobacterium tuberculosis." Handbook of Tuberculosis: Molecular Biology and Biochemistry Eds. Kaufmann and Rubin. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KgaA. 91-110. (Books and Publications: Chapter) 2008
"Iron Uptake in Mycobacteria." The Mycobacterial Cell Envelope Eds: Daffé and Reyrat. Washington, D.C.: ASM Press. 167-84. (Books and Publications: Chapter) 2008
Crick, Quadri and Brennan. "Biochemistry of the Cell Envelope of Mycobacterium tuberculosis." Handbook of Tuberculosis: Molecular Biology and Biochemistry. Eds. Kaufmann and Rubin. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KgaA. 1-20. (Books and Publications: Chapter) 2008
Ferreras, Stirrett, Lu, Ryu, Soll, Tan and Quadri. "Mycobacterial Phenolic Glycolipid Virulence Factor Biosynthesis: Mechanism and Small-molecule Inhibition of Polyketide Chain Initiation."Chemistry & Biology 15: 51-61. (Highlighted in Start-Up Magazine January.) http://www.ncbi.nlm.nih.gov/pubmed?term=18158259. (Books and Publications: Peer Reviewed Article) 2008
Stirrett, Ferreras, Jayaprakash, Sinha, Ren and Quadri. "Small Molecules With Structural Similarities to Siderophores as Novel Antimicrobials Against Mycobacterium tuberculosis and Yersinia pestis." Bioorganic & Medicinal Chemistry Letters 18: 2662-68. http://www.ncbi.nlm.nih.gov/pubmed?term=18394884. (Books and Publications: Peer Reviewed Article) 2008
Stirrett, Ferreras, Rossi, Moy, Fonseca and Quadri. "A Multicopy Suppressor Screening Approach as a Means to Identify Antibiotic Resistance Determinant Candidates in Yersinia pestis." BMC Microbiology 8: 122. (Flagged as "Highly Accessed" by BMC Microbiology.) http://www.ncbi.nlm.nih.gov/pubmed?term=18644132. (Books and Publications: Peer Reviewed Article) 2008
"Strategic Paradigm Shifts in the Antimicrobial Drug Discovery Process of the 21st Century." Infectious Disorders - Drug Targets 7: 230-37. http://www.ncbi.nlm.
Cisar, Ferreras, Soni, Quadri and Tan. "Exploiting Ligand Conformation in the Selective Inhibition of Nonribosomal Peptide Synthetase Amino Acid Adenylation With Designed Macrocyclic Small Molecules." Journal of the American Chemical Society 129: 7752-53. (Highlighted in Faculty of 1000 by Ross Weatherman and Dennis Hall: www.f1000biology.com/article/id/1087363) http://www.ncbi.nlm.nih.gov/pubmed?term=17542590. (Books and Publications: Peer Reviewed Article) 2007
Rohde and Quadri. "Functional Characterization of a Three-component Regulatory System Involved in Quorum Sensing-based Regulation of Peptide Antibiotic Production in Carnobacterium maltaromaticum." BMC Microbiology 6: 93. http://www.ncbi.nlm.nih.gov/pubmed?term=17054797. (Books and Publications: Peer Reviewed Article) 2006
Ferreras, Ryu, Di Lello, Tan and Quadri. "Small Molecule Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis and Yersinia pestis." Nature Chemical Biology 1: 29-32. (Highlighted in the "Research Highlights" section of Nature 435: 389, and in the "News of the Week" section of Chemical & Engineering News 83: 13.) http://www.ncbi.nlm.nih.gov/pubmed?term=16407990. (Books and Publications: Peer Reviewed Article) 2005
Onwueme, Vos, Zurita, Ferreras and Quadri. "The Dimycocerosate Ester Polyketide Virulence Factors of Mycobacteria." Progress in Lipid Research 44: 259-302. http://www.ncbi.nlm.nih.gov/pubmed/16115688. (Books and Publications: Peer Reviewed Article) 2005
Onwueme, Vos, Zurita, Soll and Quadri. "Identification of Phthiodiolone Ketoreductase, an Enzyme Required for Production of Mycobacterial Diacyl Phthiocerol Virulence Factors." Journal of Bacteriology 187: 4760-66. http://www.ncbi.nlm.nih.gov/pubmed/15995190. (Books and Publications: Peer Reviewed Article) 2005
Palma, Zurita, Ferreras, Worgall, Larone, Shi, Campagne and Quadri. "Pseudomonas Aeruginosa SoxR Does Not Conform to the Archetypal Paradigm for SoxR-dependent Regulation of the Bacterial Oxidative Stress Adaptive Response." Infection and Immunity 73: 2958-66. http://www.ncbi.nlm.nih.gov/pubmed/15845502. (Books and Publications: Peer Reviewed Article) 2005
Quadri and Ratledge. "Iron Metabolism in the Tubercle Bacillus and Other Mycobacteria." Tuberculosis and the Tubercle Bacillus. Eds: Cole, Eisenach, McMurray and Jacobs Jr. Washington, D.C.: ASM Press. 341-57. (Books and Publications: Chapter) 2005
Worgall, Heguy, Luettich, O'Connor, Harvey, Quadri and Crystal. "Similarity of Patterns in Gene Expression of Human Alveolar Macrophages Evoked by Pseudomonas aeruginosa and Burkholderia cepacia." Infection and Immunity 73: 5262-68. http://www.ncbi.nlm.nih.gov/pubmed/16041053. (Books and Publications: Peer Reviewed Article) 2005
Buglino, Onwueme, Ferreras, Quadri and Lima. "Crystal Structure of PapA5, a Phthiocerol Dimycocerosyl Transferase From Mycobacterium tuberculosis." Journal of Biological Chemistry 279: 30634-42. http://www.ncbi.nlm.nih.gov/pubmed/
Onwueme, Ferreras, Buglino, Lima and Quadri. "Mycobacterial Polyketide Associated Proteins Are Acyltransferases: Proof of Principle With Mycobacterium tuberculosis PapA5." Proceedings of the National Academy of Sciences USA 101: 4608-13. http://www.ncbi.nlm.nih.gov/pubmed/15070765. (Books and Publications: Peer Reviewed Article) 2004
Palma, DeLuca, Worgall and Quadri. "Transcriptome Analysis of the Response of Pseudomonas aeruginosa to Hydrogen Peroxide." Journal of Bacteriology 186: 248-52. http://www.ncbi.nlm.nih.gov/pubmed/14679246. (Books and Publications: Peer Reviewed Article) 2004
"Regulation of Class II Bacteriocin Production by Cell-cell Signaling." Journal of Microbiology 41: 175-82. http://www.msk.or.kr/jsp/recent_paper.jsp. (Books and Publications: Peer Reviewed Article) 2003
Palma, Worgall and Quadri. "Transcriptome Aanalysis of the Pseudomonas aeruginosa Response to Iron." Archives of Microbiology 180: 374-79. http://www.ncbi.nlm.nih.gov/pubmed/14513207. (Books and Publications: Peer Reviewed Article) 2003
"Regulation of Antimicrobial Peptide Production by Autoinducer-mediated Quorum Sensing in Lactic Acid Bacteria." Antonie Van Leeuwenhoek 82: 133-45. http://www.ncbi.nlm.nih.gov/pubmed/12369185. (Books and Publications: Peer Reviewed Article) 2002
Kleerebezem and Quadri. "Peptide Pheromone-dependent Regulation of Antimicrobial Peptide Production in Gram-positive Bacteria: A Case of Multicellular Behavior." Peptides 22: 1579-96. http://www.ncbi.nlm.nih.gov/pubmed/11587786. (Books and Publications: Peer Reviewed Article) 2001
Kleerebezem, Kuipers, de Vos, Stiles and Quadri. "A Two-component Signal-transduction Cascade in Carnobacterium piscicola LV17B: Two Signaling Peptides and One Sensor-transmitter." Peptides 22: 1597-601. http://www.ncbi.nlm.nih.gov/
"Assembly of Aryl-capped Siderophores by Modular Peptide Synthetases and Polyketide Synthases." Molecular Microbiology 37: 1-12. http://www.ncbi.nlm.
Franz, Worobo, Quadri, Schillinger, Holzapfel, Vederas and Stiles. "Atypical Genetic Locus for Enterocin B Production in Enterococcus faecium BFE 900." Applied and Environmental Microbiology 65: 2170-78. http://www.ncbi.nlm.nih.gov/pubmed/
Quadri, Keating, Patel, and Walsh. "Assembly of the Pseudomonas Aeruginosa Nonribosomal Peptide Siderophore Pyochelin: In vitro Reconstitution of aryl-4,2-bisthiazoline synthetase Activity From PchD, PchE and PchF." Biochemistry 38: 14941-54. http://www.ncbi.nlm.nih.gov/pubmed/10555976. (Books and Publications: Peer Reviewed Article) 1999
Quadri, Sello, Keating, Weinreb and Walsh. "Identification of a Mycobacterium Tuberculosis Gene Cluster Encoding the Biosynthetic Enzymes for Assembly of the Virulence-conferring Siderophore Mycobactin." Chemistry & Biology 5: 631-45. http://www.ncbi.nlm.nih.gov/pubmed/9831524. (Books and Publications: Peer Reviewed Article) 1998
Quadri, Weinreb, Lei, Nakano, Zuber and Walsh. "Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases." Biochemistry 37: 1585-95. http://www.ncbi.nlm.nih.gov/
Weinreb, Quadri, Walsh and Zuber. "Stoichiometry and Specificity of in vitro Phosphopantetheinylation and Aminoacylation of the Valine-activating Module of Surfactin Synthetase." Biochemistry 37: 1575-84. http://www.ncbi.nlm.nih.gov/
Kleerebezem, Quadri, Kuipers and de Vos. "Quorum Sensing by Peptide Pheromones and Two-component Signal-transduction Systems in Gram-positive Bacteria." Molecular Microbiology 24: 895-904. http://www.ncbi.nlm.nih.gov/
Quadri, Kleerebezem, Kuipers, de Vos, Roy, Vederas and Stiles. "Characterization of a Locus From Carnobacterium piscicola LV17B Involved in Bacteriocin Production and Immunity: Evidence for Global Inducer-mediated Transcriptional Regulation." Journal of Bacteriology 179: 6163-71. http://www.ncbi.nlm.nih.gov/pubmed/9324267. (Books and Publications: Peer Reviewed Article) 1997
Quadri, Yan, Stiles and Vederas. "Effect of Amino Acid Substitutions on the Activity of Carnobacteriocin B2. Overproduction of the Antimicrobial Peptide, Its Engineered Variants and Its Precursor in Escherichia coli." Journal of Biological Chemistry. 272: 3384-88. http://www.ncbi.nlm.nih.gov/pubmed/9013580. (Books and Publications: Peer Reviewed Article) 1997
Walsh, Gehring, Weinreb, Quadri and Flugel. "Post-translational Modification of Polyketide and Nonribosomal Peptide Synthases." Current Opinion in Chemical Biology 1: 309-15. http://www.ncbi.nlm.nih.gov/pubmed/9667867. (Books and Publications: Peer Reviewed Article) 1997
Quadri, Sailer, Terebiznik, Roy, Vederas and Stiles. "Characterization of the Protein Conferring Immunity to the Antimicrobial Peptide Carnobacteriocin B2 and Expression of Carnobacteriocins B2 and BM1." Journal of Bacteriology 177: 1144-51. http://www.ncbi.nlm.nih.gov/pubmed/7868585. (Books and Publications: Peer Reviewed Article) 1995
Quadri, Sailer, Roy, Vederas and Stiles. "Chemical and Genetic Characterization of Bacteriocins Produced by Carnobacterium piscicola LV17B." Journal of Biological Chemistry 269: 12204-11. http://www.ncbi.nlm.nih.gov/pubmed/8163526 (Books and Publications: Peer Reviewed Article) 1994
Quadri and Giulietti. "Effect of Elicitation on the Accumulation of Solasodine by Immobilized Cells of Solanum eleagnifolium Cav." Enzyme and Microbial Technology 15: 1074-77. http://www.ncbi.nlm.nih.gov/pubmed/7764297. (Books and Publications: Peer Reviewed Article) 1993
Creative Work
Tan, Quadri, et al. Patents, anti-microbial agents and uses thereof: (1) US Patent Appl. 11/911,525, filed Oct. 12, 2007; (2) PCT Intl. Patent Appl. PCT/US2006/014,394, filed April 14, 2006, published Oct. 26, 2006 as WO/2006/113,615; (3) US Prov. Patent Appl. 60/671,994, filed April 15, 2005. 2005-07. 2005
Awards, Honors and Fellowships
PSC-CUNY Research Award # 66485-00 44, for "Initial Investigation Into the Mechanism of Acyl Intermediate Transfer During Biosynthesis of Mmycobacterial Dimycocerosate Esters." Principal investigator. 2013-14. (Grants and Fellowships) 2013
NIH 2R01GM100477-05A1 grant, for "Rational Design of Adenylation Enzyme Inhibitors." Co-investigator. 2012-16. (Grants and Fellowships) 2012
The Potts Memorial Foundation Grant, for "Influence of Mycobacterial Outer Membrane's Components on Drug Susceptibility." Principal investigator. 2011-12. (Grants and Fellowships) 2011
NSF MRI-R2 (Major Equipment Grant), for "Acquisition of a Plasmon Resonance Spectrometer." Co-principal investigator. (Grants and Fellowships) 2010
NIH R01AI075092-01A1 grant, for "Mycobacterial Siderophores: Assembly, Assembly Inhibition, and Role in Virulence." Principal investigator. 2009-11. (Grants and Fellowships) 2009
NIH R21 AI079489-01 grant, for "Biosynthesis and Transbilayer Flipping of Mycobacterial PIM Glycolipids." Co-investigator. 2008-10. (Grants and Fellowships) 2008
NIH R01 AI068038-01A2 grant, for "Siderophore Biosynthesis Inhibitors as New Antibiotics for Biodefense." Co-investigator. 2007-12. (Grants and Fellowships) 2007
NIH U54 AI057158-05 grant, for "Novel Antibiotics Targeting Bacterial Adenylation Enzymes." Subcontractor. 2007-08. (Grants and Fellowships) 2007
NIH R01 AI069209-01 grant, for "Mycobacterial PDIM/PGL: Synthesis Pathway and Inhibition." Principal investigator. 2006-11. (Grants and Fellowships) 2006
NIH R56 AI068038-01A1 grant, for "Siderophore Biosynthesis Inhibitors as New Antibiotics for Biodefense." Co-investigator. 2006-07. (Grants and Fellowships) 2006
NIH R21AI063384-01A1 grant, for "Virulence Conferring Siderophore Biosynthesis Inhibitors." Principal investigator, 2005-07. (Grants and Fellowships) 2005
Award Program Recognition, Program Projects and Center Grants, Weill Medical College of Cornell University. (Awards and Honors) 2003
NIH P01 AI056293-01 grant, for "Novel M. tuberculosis and Y. pestis Growth Inhibitors." Project 4 leader, 2003-07. (Grants and Fellowships) 2003
Cystic Fibrosis Association grant, for "Deconvoluting the Biosynthesis of Virulence Conferring Siderophores From P. aeruginosa." Principal investigator, 2001-03. (Grants and Fellowships) 2001
Cystic Fibrosis Foundation Therapeutics grant, for "Pseudomonas and Human Cell Gene Expression in Cystic Fibrosis." Principal investigator, 2001-04. (Grants and Fellowships) 2001
NYC Speaker's Fund for Biomedical Research grant, for "Biosynthesis of Virulence Conferring Siderophores from M. tuberculosis." Principal investigator. 2000-03. (Grants and Fellowships) 2000
Potts Memorial Foundation grant, for "Structural Studies on MbtA, a Key Enzyme Required for Biosynthesis of the Siderophore Mycobactin From M. tuberculosis." Principal investigator. (Grants and Fellowships) 2000
Stavros Niarchos Scholar, Stavros Niarchos Foundation, Weill Medical College of Cornell University. (Awards and Honors) 1999
Diploma de Honor, Class of 1989, B.Sc., Buenos Aires University. (Awards and Honors) 1998
Elizabeth Russel MacEachran Research Scholarship, University of Alberta, Canada. (Awards and Honors) 1994
University of Alberta Ph.D. Research Scholarship. (Awards and Honors) 1992
Buenos Aires University Research Scholarship for Graduate Students. (Awards and Honors) 1990
International Association for the Exchange of Students Scholarship. (Awards and Honors) 1990
Buenos Aires University Research Scholarship for Undergraduate Students. (Awards and Honors) 1988
Research Activities
Quadri's lab applies multidisciplinary approaches to: (1) investigate the biosynthesis of mycobacterial siderophores (iron-chelating compounds); (2) elucidate the biosynthesis of mycobacterial outer-membrane components called DIMs; and (3) develop compounds with utility as leads for drug development or chemical biology tools. There are over 100 Mycobacterium spp., some of which cause serious diseases whereas others play roles in natural attenuation of contaminated sites and represent potential agents for bioremediation. Siderophores are key elements of iron-uptake systems utilized by pathogenic and free living mycobacteria. DIMs are lipidic virulence factors of several clinically relevant mycobacteria. DIMs play roles in pathogenicity by virtue of their immunomodulatory properties or their ability to cause nerve degeneration. Drugs that inhibit synthesis of siderophores or DIMs may have applications in the treatment of mycobacterial diseases. 2010
Conferences, Seminars and Symposiums
Institute for Tuberculosis Research, Department of Medicinal Chemistry & Pharmacognosy, College of Pharmacy, University of Illinois at Chicago. (Conferences, Seminars and Symposiums: Invited Talk) 2012
Annual Meeting of the American Society for Biochemistry and Molecular Biology. Washington, D.C., April 9-13. (Conferences, Seminars and Symposiums: Invited Talk) 2011
Third Annual Regional Tuberculosis Conference in recognition of World TB Day. David Axelrod Institute, Wadsworth Center, New York State Department of Health. Albany, N.Y., March 24-25. (Conferences, Seminars and Symposiums: Invited Talk) 2011
David Axelrod Institute, Wadsworth Center, New York State Department of Health. Albany, N.Y., September. (Conferences, Seminars and Symposiums: Invited Talk) 2010
Department of Chemistry, Rutgers University. Newark, N.J. (Conferences, Seminars and Symposiums: Invited Talk) 2010
World Tuberculosis Day Symposium, Public Health Research Institute, New Jersey Medical School. Newark, N.J., March 23-24. (Conferences, Seminars and Symposiums: Invited Talk) 2010
Department of Molecular Medicine, University of South Florida Medical School. Tampa, Fla. (Conferences, Seminars and Symposiums: Invited Talk) 2009
Second Natural Products Zing Conference. Bolans Village, Antigua and Barbuda, March 1-4. (Conferences, Seminars and Symposiums: Invited Talk) 2009
Society for General Microbiology Meeting, Novel Therapeutics Symposium. Harrogate, United Kingdom. (Conferences, Seminars and Symposiums: Invited Talk) 2009
Zicklin Chair Seminar Speaker, Department of Biology, Brooklyn College. (Conferences, Seminars and Symposiums: Invited Talk) 2009
Department of Biochemistry and Molecular Biology, New York Medical College. Valhalla, N.Y. (Conferences, Seminars and Symposiums: Invited Talk) 2008
Department of Microbiology, University of Massachusetts Amherst. Amherst, Mass. (Conferences, Seminars and Symposiums: Invited Talk) 2008
Fifth National RCE Meeting Program. Chicago. (Conferences, Seminars and Symposiums: Invited Talk) 2008
Seventh U.S.-Japan Seminar on the Biosynthesis of Natural Products: Enzymology, Structural Biology and Drug Discovery. La Jolla, Calif. (Conferences, Seminars and Symposiums: Invited Talk) 2008
Department of Chemistry, Stony Brook University. Stony Brook, N.Y. (Conferences, Seminars and Symposiums: Invited Talk) 2007
Novartis Vaccines & Diagnostics S.R.L. Siena, Italy. (Conferences, Seminars and Symposiums: Invited Talk) 2007
Public Health Research Institute and Department of Microbiology and Molecular Genetics, New Jersey Medical School. Newark, N.J. (Conferences, Seminars and Symposiums: Invited Talk) 2007
The American Society for Microbiology 107th General Meeting. Toronto. (Conferences, Seminars and Symposiums: Invited Talk) 2007
Department of Immunology and Infectious Diseases, Harvard Medical School. Boston. (Conferences, Seminars and Symposiums: Invited Talk) 2006
Department of Microbiology and Immunology, East Carolina University School of Medicine. Greenville, N.C. (Conferences, Seminars and Symposiums: Invited Talk) 2006
Department of Microbiology, Immunology and Pathology, CVMBS, Colorado State University. Fort Collins, Colo. (Conferences, Seminars and Symposiums: Invited Talk) 2006
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School. Worcester, Mass. (Conferences, Seminars and Symposiums: Invited Talk) 2006
Laboratory of Genetics and Microbial Ecology, Department of Biological Chemistry, University of Buenos Aires. (Conferences, Seminars and Symposiums: Invited Talk) 2004
AstraZeneca R&D Boston. Waltham, Mass. (Conferences, Seminars and Symposiums: Invited Talk) 2003
Department of Genetics, University of Georgia. Athens, Ga. (Conferences, Seminars and Symposiums: Invited Talk) 2003
Institute of Microbiology, Seoul National University. Seoul, South Korea. (Conferences, Seminars and Symposiums: Invited Talk) 2003
International Meeting of Microbiological Society of Korea. Chunchon, South Korea. (Conferences, Seminars and Symposiums: Invited Talk) 2003
Albany Molecular Research, Inc. Albany, N.Y. (Conferences, Seminars and Symposiums: Invited Talk) 2002
Center on Bioterrorism Infectious Disease and Genetics Discussion Group. Academic Medicine Development Company Foundation, Inc. New York. (Conferences, Seminars and Symposiums: Invited Talk) 2002
Harvard Medical School-New York Tuberculosis Discussion Group. Harvard School of Public Health. Boston. (Conferences, Seminars and Symposiums: Invited Talk) 2002
Tuberculosis Research Section, Laboratory of Host Defenses, National Institutes of Health. Rockville, Md. (Conferences, Seminars and Symposiums: Invited Talk) 2002
Second Argentine-American Medical Congress. New York. (Conferences, Seminars and Symposiums: Invited Talk) 2001
Twelfth International Symposium for Biology of Actinomycetes. Vancouver, British Columbia, Canada. (Conferences, Seminars and Symposiums: Invited Talk) 2001
Harvard Medical School-New York Tuberculosis Discussion Group. Harvard School of Public Health. Boston. (Conferences, Seminars and Symposiums: Invited Talk) 2000
Molecular Approaches to Tuberculosis Workshop. Madrid. (Conferences, Seminars and Symposiums: Invited Talk) 2000
The Rockefeller University. New York. (Conferences, Seminars and Symposiums: Invited Talk) 2000
Harvard-New York Tuberculosis Meeting. Harvard School of Public Health. Boston. (Conferences, Seminars and Symposiums: Invited Talk) 1999
Molecular Genetics Unit, Ramon y Cajal Hospital. Madrid. (Conferences, Seminars and Symposiums: Invited Talk) 1996
Fifth Symposium on Lactic Acid Bacteria: Genetics, Metabolism and Application. Valdohven, the Netherlands. (Conferences, Seminars and Symposiums: Invited Talk) 1995
International Meeting on Bacteriocins of Lactic Acid Bacteria: Applications and Fundaments. Banff, Alberta, Canada. (Conferences, Seminars and Symposiums: Invited Talk) 1995
NIZO Food Research Institute. The Netherlands. (Conferences, Seminars and Symposiums: Invited Talk) 1995
Department of Biological Sciences, Univesity of Alberta, Canada. (Conferences, Seminars and Symposiums: Invited Talk) 1993
Professional Leadership
Editorial board member, Archives of Clinical Microbiology. (http://imedpub.com/ojs/index.php/acmicrob/index). 2009-present. (Professional Leadership: Organizational Leadership Position) 2009
Standing member, Drug Discovery and Mechanisms of Antimicrobial Resistance Study Section, NIH. 2009-present. (Professional Leadership: Committee Service) 2009
Symposium co-convener, "The Interface Between Microbial Pathogenesis and Chemical Biology." The American Society for Microbiology 107th General Meeting. Toronto. (Professional Leadership: Organizational Leadership Position) 2007
Temporary (ad hoc) member, 13 NIH special emphasis panels / study sections / review groups, 2006-09. (Professional Leadership: Committee Service) 2006
Reviewer (ad hoc), ACS Chemical Biology, Annals of Internal Medicine, Archives of Microbiology, Bioorganic & Medicinal Chemistry Letters, BMC Genomics, Chembiochem, Chemistry and Biology, Eukaryotic Cell, European Journal of Biochemistry, FEBS Journal, FEMS Microbiology Reviews, Food Microbiology, Journal of Bacteriology, Journal of Experimental Medicine, Journal of Proteome Research, Letters in Applied Microbiology, Microbiology, Microbiology and, Molecular Biology Reviews, Molecular Microbiology, Nature Chemical Biology, Naturwissenschaften, Peptides and Proceedings of the National Academy of Sciences USA, 1999-present. (Professional Leadership: Public Service) 1999
